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[NMR paper] Gradual Increase in Inflammation-Linked Glycoproteins and a Proatherogenic Lipoprotein Profile in the Early Stages of Psychosis as Characterized by 1H NMR Blood Analysis
Jun 25, 2023 - 9:09 PM - by nmrlearner
nmrlearner's Avatar Gradual Increase in Inflammation-Linked Glycoproteins and a Proatherogenic Lipoprotein Profile in the Early Stages of Psychosis as Characterized by 1H NMR Blood Analysis

Minimally invasive prognostic markers of inflammation and dyslipidemia in individuals with a risk of psychosis, also called "at-risk mental state" (ARMS), or in the first episode of psychosis (FEP) are of utmost clinical importance to prevent cardiovascular disorders. We analyzed the plasma concentration of inflammation-linked glycoproteins (Glycs) and lipoprotein subclasses by proton nuclear magnetic resonance (ąH NMR) in a single acquisition. Study participants were healthy controls (HCs, N =...

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In-droplet hydrogen–deuterium exchange to examine protein ... - John Wiley
Jun 24, 2023 - 6:07 PM - by nmrlearner
nmrlearner's Avatar In-droplet hydrogen–deuterium exchange to examine protein ... - John Wiley

In-droplet hydrogen–deuterium exchange to examine protein ... John Wiley Read here
0 Replies | 147 Views
Novel Machining Microscale Diamond Rotors Could Improve Protein Studies - India Education Diary
Jun 24, 2023 - 2:54 AM - by nmrlearner
nmrlearner's Avatar Novel Machining Microscale Diamond Rotors Could Improve Protein Studies - India Education Diary

Novel Machining Microscale Diamond Rotors Could Improve Protein Studies India Education Diary Read here
0 Replies | 175 Views
Structures of Large Protein Complexes Determined by Nuclear Magnetic Resonance Spectroscopy - Annual Reviews
Jun 22, 2023 - 1:21 PM - by nmrlearner
nmrlearner's Avatar Structures of Large Protein Complexes Determined by Nuclear Magnetic Resonance Spectroscopy Annual Reviews
Structures of Large Protein Complexes Determined by Nuclear Magnetic Resonance Spectroscopy - Annual Reviews
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0 Replies | 165 Views
Improved spectral resolution of [13C,1H]-HSQC spectra of aromatic amino acid residues in proteins produced by cell-free synthesis from inexpensive 13C-labelled precursors
Jun 20, 2023 - 9:01 PM - by nmrlearner
nmrlearner's Avatar Improved spectral resolution of [13C,1H]-HSQC spectra of aromatic amino acid residues in proteins produced by cell-free synthesis from inexpensive 13C-labelled precursors

Abstract

Cell-free protein synthesis using eCells allows production of amino acids from inexpensive 13C-labelled precursors. We show that the metabolic pathway converting pyruvate, glucose and erythrose into aromatic amino acids is maintained in eCells. Judicious choice of 13C-labelled starting material leads to proteins, where the sidechains of aromatic amino acids display [13C,1H]-HSQC cross-peaks free of one-bond 13Câ??13C couplings. Selective 13C-labelling of tyrosine and phenylalanine residues is achieved simply by using different compositions of the reaction buffers.



Source: Journal of Biomolecular NMR
0 Replies | 207 Views
Global Protein Crystallization And Crystallography Market Size and ... - Reedley Exponent
Jun 20, 2023 - 9:01 PM - by nmrlearner
nmrlearner's Avatar Global Protein Crystallization And Crystallography Market Size and ... - Reedley Exponent

Global Protein Crystallization And Crystallography Market Size and ... Reedley Exponent Read here
0 Replies | 193 Views
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