BioNMR
NMR aggregator & online community since 2003
BioNMR    
Learn or help to learn NMR - get free NMR books!
 

Home Forums Wiki NMR feeds Downloads Register Today's Posts



Jobs Groups Conferences Literature Pulse sequences Software forums Programs Sample preps Web resources BioNMR issues


» Online Users: 150
0 members and 150 guests
No Members online
Most users ever online was 1,278, 01-09-2024 at 07:38 AM.
» Welcome!

Welcome, NMR world!


Our visitors map.


» Log in
User Name Not a member yet?
Register Now!
Password
3D Protein Structure Analysis Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2017-2027 - Yahoo Finance
Jun 14, 2023 - 10:14 PM - by nmrlearner
nmrlearner's Avatar 3D Protein Structure Analysis Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2017-2027 - Yahoo Finance

3D Protein Structure Analysis Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2017-2027 Yahoo Finance Read here
0 Replies | 132 Views
AlphaFold: A Pioneering AI Approach to Protein Structure Prediction - CityLife
Jun 14, 2023 - 10:14 PM - by nmrlearner
nmrlearner's Avatar AlphaFold: A Pioneering AI Approach to Protein Structure Prediction - CityLife

AlphaFold: A Pioneering AI Approach to Protein Structure Prediction CityLife Read here
0 Replies | 154 Views
Capillary electrophoresis-mass spectrometry for protein analyses ... - John Wiley
Jun 14, 2023 - 10:14 PM - by nmrlearner
nmrlearner's Avatar Capillary electrophoresis-mass spectrometry for protein analyses ... - John Wiley

Capillary electrophoresis-mass spectrometry for protein analyses ... John Wiley Read here
0 Replies | 163 Views
[NMR paper] E. coli "Stablelabel" S30 lysate for optimized cell-free NMR sample preparation
Jun 14, 2023 - 10:14 PM - by nmrlearner
nmrlearner's Avatar E. coli "Stablelabel" S30 lysate for optimized cell-free NMR sample preparation

Cell-free (CF) synthesis with highly productive E. coli lysates is a convenient method to produce labeled proteins for NMR studies. Despite reduced metabolic activity in CF lysates, a certain scrambling of supplied isotope labels is still notable. Most problematic are conversions of ^(15)N labels of the amino acids L-Asp, L-Asn, L-Gln, L-Glu and L-Ala, resulting in ambiguous NMR signals as well as in label dilution. Specific inhibitor cocktails suppress most undesired conversion reactions, while...

More...
0 Replies | 113 Views
[NMR paper] Improved methodology for protein NMR structure calculation using hydrogen bond restraints and ANSURR validation: The SH2 domain of SH2B1
Jun 14, 2023 - 10:14 PM - by nmrlearner
nmrlearner's Avatar Improved methodology for protein NMR structure calculation using hydrogen bond restraints and ANSURR validation: The SH2 domain of SH2B1

Protein structures calculated using NMR data are less accurate and less well-defined than they could be. Here we use the program ANSURR to show that this deficiency is at least in part due to a lack of hydrogen bond restraints. We describe a protocol to introduce hydrogen bond restraints into the structure calculation of the SH2 domain from SH2B1 in a systematic and transparent way and show that the structures generated are more accurate and better defined as a result. We also show that ANSURR...

More...
0 Replies | 109 Views
[NMR paper] Fibrils Emerging from Droplets: Molecular Guiding Principles behind Phase Transitions of a Short Peptide-Based Condensate Studied by Solid-State NMR
Jun 14, 2023 - 10:14 PM - by nmrlearner
nmrlearner's Avatar Fibrils Emerging from Droplets: Molecular Guiding Principles behind Phase Transitions of a Short Peptide-Based Condensate Studied by Solid-State NMR

Biochemical reactions occurring in highly crowded cellular environments require different means of control to ensure productivity and specificity. Compartmentalization of reagents by liquid-liquid phase separation is one of these means. However, extremely high local protein concentrations of up to 400 mg/ml can result in pathological aggregation into fibrillar amyloid structures, a phenomenon that has been linked to various neurodegenerative diseases. Despite its relevance, the process of...

More...
0 Replies | 107 Views
» Stats
Members: 3,202
Threads: 25,764
Posts: 26,150
Top Poster: nmrlearner (23,208)
Welcome to our newest member, bpadmanabhan
Powered by vBadvanced CMPS v3.2.2

All times are GMT. The time now is 01:05 PM.



Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
vBCredits II Deluxe v1.2.0 Copyright © 2010 DragonByte Technologies
Copyright, BioNMR.com, 2003-2013
Search Engine Friendly URLs by vBSEO 3.6.0

Map