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[NMR paper] NMR tools to detect protein allostery |
Mar 02, 2024 - 3:40 PM - by nmrlearner
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NMR tools to detect protein allostery
Allostery is a fundamental mechanism of cellular homeostasis by intra-protein communication between distinct functional sites. It is an internal process of proteins to steer interactions not only with each other but also with other biomolecules such as ligands, lipids, and nucleic acids. In addition, allosteric regulation is particularly important in enzymatic activities. A major challenge in structural and molecular biology today is unraveling allosteric sites in proteins, to elucidate the...
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