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[ASAP] Solid-State NMR Reveals Asymmetric ATP Hydrolysis in the Multidrug ABC Transporter BmrA
Jul 04, 2022 - 5:37 AM - by nmrlearner
nmrlearner's Avatar [ASAP] Solid-State NMR Reveals Asymmetric ATP Hydrolysis in the Multidrug ABC Transporter BmrA

Denis Lacabanne, Thomas Wiegand, Margot Di Cesare, Ce?dric Orelle, Matthias Ernst, Jean-Michel Jault, Beat H. Meier, and Anja Bo?ckmann



Journal of the American Chemical Society
DOI: 10.1021/jacs.2c04287



Source: Journal of the American Chemical Society
0 Replies | 72 Views
New insights of how the HIV-1 assembles and incorporates the Env protein - EurekAlert
Jul 04, 2022 - 5:37 AM - by nmrlearner
nmrlearner's Avatar New insights of how the HIV-1 assembles and incorporates the Env protein EurekAlert
New insights of how the HIV-1 assembles and incorporates the Env protein - EurekAlert
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0 Replies | 38 Views
Computer Simulations of Proteins Help Unravel Why Chemotherapy Resistance Occurs | | SBU News - Stony Brook News
Jul 04, 2022 - 5:37 AM - by nmrlearner
nmrlearner's Avatar Computer Simulations of Proteins Help Unravel Why Chemotherapy Resistance Occurs | | SBU News - Stony Brook News

Computer Simulations of Proteins Help Unravel Why Chemotherapy Resistance Occurs | | SBU News Stony Brook News Read here
0 Replies | 44 Views
Mutations linked to neurological disease enhance self-association of low-complexity protein sequences - Science
Jul 01, 2022 - 10:59 AM - by nmrlearner
nmrlearner's Avatar Mutations linked to neurological disease enhance self-association of low-complexity protein sequences Science
Mutations linked to neurological disease enhance self-association of low-complexity protein sequences - Science
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0 Replies | 42 Views
[NMR paper] Production and Preparation of Isotopically Labeled Human Membrane Proteins in Pichia pastoris for Fast-MAS-NMR Analyses
Jul 01, 2022 - 10:59 AM - by nmrlearner
nmrlearner's Avatar Production and Preparation of Isotopically Labeled Human Membrane Proteins in Pichia pastoris for Fast-MAS-NMR Analyses

Membrane proteins (MPs) comprise about one-third of the human proteome, playing critical roles in many physiological processes and associated disorders. Consistently, they represent one of the largest classes of targets for the pharmaceutical industry. Their study at the molecular level is however particularly challenging, resulting in a severe lack of structural and dynamic information that is hindering their detailed functional characterization and the identification of novel potent drug...

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0 Replies | 70 Views
[NMR paper] Solid-state NMR 13C and 15*N resonance assignments of Vibrio sp. SemiSWEET transporter in lipid bilayers
Jul 01, 2022 - 10:59 AM - by nmrlearner
nmrlearner's Avatar Solid-state NMR 13C and 15*N resonance assignments of Vibrio sp. SemiSWEET transporter in lipid bilayers

The Sugar Will Eventually be Exported Transporter (SWEET) family is a new class of transporters that plays crucial roles in the cellular sugar transport process. Their bacterial homologs, known as SemiSWEETs, are among the smallest transporters and can be used as a prototype for studying the biological properties of sugar transporters. Here, a set of dipolar-based multidimensional solid-state NMR spectra were employed to investigate the structure of Vibrio sp. SemiSWEET (Vs-SemiSWEET)...

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0 Replies | 42 Views
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