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Post Doc Toulouse |
Dec 09, 2010 - 10:44 PM - by nmrlearner
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Post Doc Toulouse
Post doctoral position announcement:
Characterisation of cholesterol – GPCR interactions by solid state NMR
As part of an Initial Training Network on the “Structural Biology of Membrane Proteins” (Marie Curie EU program SBMPs, http://www.sbmp-itn.eu), an Experienced Researcher position is available starting from 2011 in the group headed by Pr Alain Milon, “NMR and protein – membrane interactions”, Institute of Pharmacology and Structural Biology, Toulouse, France (http://www.ipbs.fr/english/teams/milon/index.htm).
G-protein coupled receptors (GPCRs) are playing a major role in signal transduction in eukaryotic cells and as such, they are of utmost pharmacological importance, being the target of about half of the major drugs currently used (1). It has been shown for several years that the lipidic environment, and in particular the sterol composition of membrane may influence the functional activation of GPCRs (2-4), and a specific cholesterol binding site has been found in the X-ray structure of the human b2 adrenergic receptor (5). Although the precise location of these cholesterol molecules bound to a GPCR are now known, much remains to be understood about their functional role and the way they actually modulate ligand binding and receptor activation. In particular the dynamics of exchange between bulk membrane cholesterol and receptor bound... [Read More]
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0 Replies | 2,522 Views
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Group Leader Positions – Bio NMR Brno |
Dec 09, 2010 - 10:44 PM - by nmrlearner
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Group Leader Positions – Bio NMR Brno
Two Group Leader Positions – Bio NMR, Central European Institute of Technology, Brno, Czech Republic
We are looking for two group leaders in the field of Bio-NMR in Structural Biology Research Program to accept the challenge of starting a world-class research group
We are recruiting two internationally established scientists to set up independent world-class research groups in the field of Bio-NMR spectroscopy in a highly inter-disciplinary setting. You will be part of the Central European Institute of Technology in Brno, Czech Republic (www.ceitec.eu). The institute will host 600 scientists and state-of-the-art equipped laboratories. The campus receives funding as a European Centre of Excellence, with a variety of international partner institutes.
Structural Biology Research Program will run core facilities for X-ray crystallography, high-end cryo electron microscopy and tomography, studies of biomolecular interactions, and high-field NMR spectroscopy. CEITEC will host also high throughput -omics facilities. Genomics and Proteomics of Plant Systems, Molecular Medicine, Molecular Veterinary Medicine, and Brain and Mind Research represent other Life Science Research Programs of CEITEC. High-field NMR Core Facility will be equipped with six 500 – 950 MHz NMR systems. Group resources include funds for post-doc positions, personnel and running... [Read More]
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0 Replies | 3,253 Views
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Post-Doc Position at the MPI for chemical Ecology in Jena |
Dec 01, 2010 - 8:36 PM - by nmrlearner
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Post-Doc Position at the MPI for chemical Ecology in Jena
Post-Doc Position at the MPI for chemical Ecology in Jena
A postdoctoral NMR position is available at the NMR laboratory of the Max Planck Institute for chemical Ecology, Jena (Germany) (http://www.ice.mpg.de). Our major focus is solution-state NMR of natural products (small molecules) with ecological implications. The laboratory is equipped with three Bruker spectrometers (500 MHz with a TCI cryoprobe and optional LC-SPE-NMR coupling; 500 MHz with full automation; 400 MHz optionally equippped with a microimaging probe, a HR-MAS probe, or diverse probes for NMR of liquid samples including a selective 19F probe).
Candidates should have a Ph.D. in chemistry, biochemistry, or physics. Previous NMR experience (preferentially biological liquids), interest in ecological projects and the willingness to cooperate with biologist are required.
The Max Planck Institute is an equal-opportunity employer and especially encourages women to apply. Applications from handicapped persons will be favored when all other qualifications are equal.
Please send your CV, representative publications, and recommendation addresses / letters to Bernd Schneider (schneider@ice.mpg.de).
... [Read More]
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0 Replies | 2,585 Views
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Post-Doc fellowship in NMR Methods to Study Ionic Solids/liquids - Univ. of Aveiro/Lisbon (Portugal) |
Dec 01, 2010 - 8:36 PM - by nmrlearner
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Post-Doc fellowship in NMR Methods to Study Ionic Solids/liquids - Univ. of Aveiro/Lisbon (Portugal)
A 1-year postdoctoral position is available starting from January 2011, (extendable for additional 12 months) to study the “solid structure” of ionic liquids (ILs) and ionic solids (ISs) with relevance to the pharmaceutical industry. The research will be centred in the use of NMR techniques in tandem with molecular modelling to study the physical chemistry of molecular interactions in ILs and ISs. The project will be performed at the NMR centres at the Universities of Aveiro (solid state NMR) and Nova de Lisboa (liquids NMR).
The properties of pure ILs/ISs will be studied using liquid and solid-state NMR techniques. Multinuclear liquid-state NMR experiments and high-resolution solid-state NMR methods employing 1H-X heteronuclear experiments (X=19F, 31P, 13C) and triple resonance NMR experiments will be used to characterize ISs with low melting points (“solid ionic liquids”). These studies will be complemented with first principles calculation of NMR parameters and classical molecular dynamics simulations. In a later stage the solvation of different molecules of pharmaceutical interest in biocompatible ILs will be addressed.
The successful candidate will have the opportunity to work in a challenging environment having the possibility to be familiar with several experimental techniques (X-ray diffraction, vibrational spectroscopy) and how to use them in complement with NMR spectroscopy. The candidate will also have the opportunity to participate in a project of great relevance to the pharmaceutical industry and with impact in environmental issues. Aveiro is a very pleasant city near the seacoast, located between Porto... [Read More]
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0 Replies | 2,673 Views
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» News Archive |
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Title, Username, & Date |
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Solid-state NMR Postdoc, Ames Lab
12-01-2010 08:36 PM
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PhD position in Strasbourg
12-01-2010 08:36 PM
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Postdoctoral Position in NMR and molecular modeling at Paris Descartes University
12-01-2010 08:36 PM
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PhD Studentship
12-01-2010 08:36 PM
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Postdoctoral position New York
12-01-2010 08:36 PM
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Research Fellow in experimental NMR spectroscopy
12-01-2010 08:36 PM
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Nuclear Magnetic Resonance Scientist (NMR) - Cambridge: Nuclear Magnetic Resonance Sc
11-27-2010 03:50 PM
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Postdoctral Associate in solid-state NMR, Ames Laboratory, Ames Laboratory, Ames, IA,
11-23-2010 07:11 PM
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Analytical Chemist, Spectroscopy | TOTAL Petrochemicals USA, Inc.
11-22-2010 07:08 PM
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NMR Specialist - Pharmaceutical Chemistry - Cheshire - Kelly Scientific Resources - N
11-22-2010 07:08 PM
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Post-Doctorate Research Associate | University of Oklahoma
11-20-2010 06:29 AM
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ASSISTANT PROFESSOR?BIOCHEMISTRY - University of Wisconsin, La Crosse - La Crosse, WI
11-17-2010 05:53 AM
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Chemist - NMR and LC - Kelly Scientific Resources - Houston, TX, United States
11-13-2010 05:01 PM
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Analytical Chemist PhD Needed- NMR Expertise - Kelly Scientific Resources - Wilmingto
11-11-2010 04:33 PM
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Postdoctoral Research Fellow- Protein Engineering - Genentech, Inc. - United States
11-10-2010 04:10 AM
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Scientist (Technology) NMR - Genentech, Inc. - South San Francisco, CA, United States
11-10-2010 04:10 AM
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TC23 - Senior Lab Technician - Kelly Scientific Resources - Freeport, TX, United Stat
11-08-2010 02:55 PM
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Chemist - Kelly Scientific Resources - Pasadena, TX, United States
11-08-2010 02:55 PM
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Analytical Chemistry Lab Technician - Kelly Scientific Resources - Rochester, NY, Uni
11-08-2010 02:55 PM
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PhD position Victoria University of Wellington
11-05-2010 12:09 AM
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