BioNMR - Search Results

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	[NMR paper] Insights into the Structure and Dynamics of Proteins from (19)F Solution NMR Spectroscopy Insights into the Structure and Dynamics of Proteins from (19)F Solution NMR Spectroscopy ^(19)F NMR spectroscopy has recently witnessed a resurgence as an attractive analytical tool for the study of the structure and dynamics of biomolecules in vitro and in cells, despite reports of its applications in biomolecular NMR since the 1970s. The high gyromagnetic ratio, large chemical shift dispersion, and complete absence of the spin 1/2 ^(19)F nucleus from biomolecules results in background-free, high-resolution ^(19)F NMR spectra. The introduction of ^(19)F probes in a few selected... ... nmrlearner	Yesterday 11:39 PM by nmrlearner	0	4	Journal club
	[NMR paper] Selective Methods Promote Protein Solid-State NMR Selective Methods Promote Protein Solid-State NMR Solid-state nuclear magnetic resonance (ssNMR) is indispensable for studying the structures, dynamics, and interactions of insoluble proteins in native or native-like environments. While ssNMR includes numerous nonselective techniques for general analysis, it also provides various selective methods that allow for the extraction of precise details about proteins. This perspective highlights three key aspects of selective methods: selective signals of protein segments, selective recoupling, and... More... nmrlearner	Yesterday 11:39 PM by nmrlearner	0	13	Journal club
	[NMR paper] Solid-state NMR compositional analysis of sputum from people with cystic fibrosis Solid-state NMR compositional analysis of sputum from people with cystic fibrosis People with the genetic disease cystic fibrosis (CF) often have chronic airway infections and produce airway secretions called sputum. A better understanding of sputum composition is desired in order to track changes in response to CF therapeutics and to improve laboratory models for the study of CF airway infections. The glycosylated protein mucin is a primary component. Along with extracellular DNA, mucin gives rise to the high viscoelasticity of sputum, which inhibits airway clearance and is... More... nmrlearner	Yesterday 05:25 AM by nmrlearner	0	60	Journal club
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