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[ASAP] Targeted Protein Degradation via Lysosomes
Sep 23, 2022 - 6:24 AM - by nmrlearner
nmrlearner's Avatar [ASAP] Targeted Protein Degradation via Lysosomes



Biochemistry
DOI: 10.1021/acs.biochem.2c00310


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0 Replies | 66 Views
[NMR paper] ssPINE: Probabilistic Algorithm for Automated Chemical Shift Assignment of Solid-State NMR Data from Complex Protein Systems
Sep 23, 2022 - 6:24 AM - by nmrlearner
nmrlearner's Avatar ssPINE: Probabilistic Algorithm for Automated Chemical Shift Assignment of Solid-State NMR Data from Complex Protein Systems

The heightened dipolar interactions in solids render solid-state NMR (ssNMR) spectra more difficult to interpret than solution NMR spectra. On the other hand, ssNMR does not suffer from severe molecular weight limitations like solution NMR. In recent years, ssNMR has undergone rapid technological developments that have enabled structure-function studies of increasingly larger biomolecules, including membrane proteins. Current methodology includes stable isotope labeling schemes, non-uniform...

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0 Replies | 33 Views
[ASAP] Direct Detection of Reactive Gallium-Hydride Species on the Ga2O3 Surface via Solid-State NMR Spectroscopy
Sep 21, 2022 - 11:29 AM - by nmrlearner
nmrlearner's Avatar [ASAP] Direct Detection of Reactive Gallium-Hydride Species on the Ga2O3 Surface via Solid-State NMR Spectroscopy

Hongyu Chen, Pan Gao, Zhengmao Liu, Lixin Liang, Qiao Han, Zhili Wang, Kuizhi Chen, Zhenchao Zhao, Meiling Guo, Xuebin Liu, Xiuwen Han, Xinhe Bao, and Guangjin Hou



Journal of the American Chemical Society
DOI: 10.1021/jacs.2c01005



Source: Journal of the American Chemical Society
0 Replies | 64 Views
Nut consumption is associated with a shift of the NMR lipoprotein subfraction profile to a less atherogenic pattern among older individuals at high CVD risk - Cardiovascular Diabetology - Cardiovascular Diabetology
Sep 21, 2022 - 11:29 AM - by nmrlearner
nmrlearner's Avatar Nut consumption is associated with a shift of the NMR lipoprotein subfraction profile to a less atherogenic pattern among older individuals at high CVD risk - Cardiovascular Diabetology Cardiovascular Diabetology
Nut consumption is associated with a shift of the NMR lipoprotein subfraction profile to a less atherogenic pattern among older individuals at high CVD risk - Cardiovascular Diabetology - Cardiovascular Diabetology
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0 Replies | 34 Views
Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE | Molecular Psychiatry - Nature.com
Sep 21, 2022 - 11:29 AM - by nmrlearner
nmrlearner's Avatar Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE | Molecular Psychiatry - Nature.com

Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE | Molecular Psychiatry Nature.com Read here
0 Replies | 44 Views
[NMR paper] The use of time domain 1 H NMR to study proton dynamics in starch-rich foods: A review
Sep 21, 2022 - 11:29 AM - by nmrlearner
nmrlearner's Avatar The use of time domain 1 H NMR to study proton dynamics in starch-rich foods: A review

Starch is a major contributor to the carbohydrate portion of our diet. When it is present with water, it undergoes several transformations during heating and/or cooling making it an essential structure-forming component in starch-rich food systems (e.g., bread and cake). Time domain proton nuclear magnetic resonance (TD ¹ H NMR) is a useful technique to study starch-water interactions by evaluation of molecular mobility and water distribution. The data obtained correspond to changes in starch...

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0 Replies | 47 Views
What is Protein Data Bank (PDB) file? How to open it in Windows? - TheWindowsClub
Sep 20, 2022 - 1:42 PM - by nmrlearner
nmrlearner's Avatar What is Protein Data Bank (PDB) file? How to open it in Windows? - TheWindowsClub

What is Protein Data Bank (PDB) file? How to open it in Windows? TheWindowsClub Read here
0 Replies | 39 Views
[NMR paper] Monitoring bromide loss in bromoacetyl-derivatized polyribosylribitol polysaccharide in Haemophilus influenzae type b for PedvaxHIB® by capillary electrophoresis and NMR spectroscopy
Sep 20, 2022 - 1:42 PM - by nmrlearner
nmrlearner's Avatar Monitoring bromide loss in bromoacetyl-derivatized polyribosylribitol polysaccharide in Haemophilus influenzae type b for PedvaxHIB® by capillary electrophoresis and NMR spectroscopy

PedvaxHIB® is an effective pediatric vaccine for protecting infants from invasive gram-negative bacterium Haemophilus influenzae type b. It is a highly purified capsular polysaccharide, polyribosylribitol phosphate that is covalently linked to an outer membrane protein complex of Neisseria meningitidis. PRP is first derivatized with an organic linker, followed by the coupling of a butadiamine group, and then at the end terminal, a bromoacetyl group is attached for conjugation with thiolated...

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0 Replies | 66 Views
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