Unless disordered proteins is what you are after, you may want to check if the protein you want to study with NMR is actually disordered and most likely not a very good NMR target.
The following servers for prediction of disordered regions in proteins are available.
Conformational Disorder of Membrane Peptides Investigated from Solid-State NMR Linewidths and Lineshapes.
Conformational Disorder of Membrane Peptides Investigated from Solid-State NMR Linewidths and Lineshapes.
Conformational Disorder of Membrane Peptides Investigated from Solid-State NMR Linewidths and Lineshapes.
J Phys Chem B. 2011 Aug 1;
Authors: Su Y, Hong M
A challenge in the application of solid-state NMR spectroscopy to membrane proteins and peptides is the relatively broad linewidths compared to solution NMR spectra. To understand the linewidth contributions to membrane protein spectra, we have measured the inhomogeneous and homogeneous...
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08-03-2011 12:00 PM
Rapid identification of protein-protein interfaces for the construction of a complex model based on multiple unassigned signals by using time-sharing NMR measurements.
Rapid identification of protein-protein interfaces for the construction of a complex model based on multiple unassigned signals by using time-sharing NMR measurements.
Rapid identification of protein-protein interfaces for the construction of a complex model based on multiple unassigned signals by using time-sharing NMR measurements.
J Struct Biol. 2011 Apr 9;
Authors: Kodama Y, Reese ML, Shimba N, Ono K, Kanamori E, Dötsch V, Noguchi S, Fukunishi Y, Suzuki EI, Shimada I, Takahashi H
Protein-protein interactions are necessary for various cellular...
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04-20-2011 07:15 PM
[NMR paper] NMR structure of the LCCL domain and implications for DFNA9 deafness disorder.
NMR structure of the LCCL domain and implications for DFNA9 deafness disorder.
Related Articles NMR structure of the LCCL domain and implications for DFNA9 deafness disorder.
EMBO J. 2001 Oct 1;20(19):5347-53
Authors: Liepinsh E, Trexler M, Kaikkonen A, Weigelt J, Bányai L, Patthy L, Otting G
The LCCL domain is a recently discovered, conserved protein module named after its presence in Limulus factor C, cochlear protein Coch-5b2 and late gestation lung protein Lgl1. The LCCL domain plays a key role in the autosomal dominant human deafness...
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11-19-2010 08:44 PM
[NMR paper] NMR spin relaxation methods for characterization of disorder and folding in proteins.
NMR spin relaxation methods for characterization of disorder and folding in proteins.
Related Articles NMR spin relaxation methods for characterization of disorder and folding in proteins.
J Mol Graph Model. 2001;19(1):3-12
Authors: Bracken C
The flexibility and dynamics of proteins directly influence the processes of protein folding, recognition, and function. NMR spin relaxation methods are used to assess the dynamics and mobility of proteins, for fast ps and ns motions as well as slower microsecond and ms events. The degree of protein...
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11-19-2010 08:32 PM
Nobel Laureate Presents Chronic Wasting Disease Lecture at UW - University of Wyoming
Nobel Laureate Presents Chronic Wasting Disease Lecture at UW - University of Wyoming News
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University of Wyoming News
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Nobel Laureate Presents Chronic Wasting Disease Lecture at UW
University of Wyoming News
His research interests include molecular structural biology, protein science and structural genomics with an emphasis on using nuclear magnetic resonance ...
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