News-Medical.net What is Structural Genomics? News-Medical.net
The purified and crystallized proteins can be analyzed with X-ray crystallography or Nuclear Magnetic Resonance. This allows the structure of every protein encoded by the genome to be determined. Ab initio modeling: information about the protein ...
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[NMR paper] NMR in structural genomics to increase structural coverage of the protein universe.
NMR in structural genomics to increase structural coverage of the protein universe.
NMR in structural genomics to increase structural coverage of the protein universe.
FEBS J. 2016 May 7;
Authors: Serrano P, Dutta SK, Proudfoot A, Mohanty B, Susac L, Martin B, Geralt M, Jaroszewski L, Godzik A, Elsliger M, Wilson IA, Wüthrich K
Abstract
For more than a decade, the Joint Center for Structural Genomics (JCSG; www . jcsg . org) worked toward increased three-dimensional structure coverage of the protein universe. This coordinated...
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05-08-2016 12:42 PM
[NMR900 blog] ICSG 2011: International Conference on Structural Genomics
ICSG 2011: International Conference on Structural Genomics
Dear Colleague, We hope that you are planning to join us in Toronto, Canada for the International Conference on Structural Genomics 2011 which will be held on May 10-14, 2011. We have an excellent scientific program prepared which includes both oral and poster presentations (scientific program). Participants will also enjoy the fabulous view of the city of Toronto during the banquet to be held at the revolving 360 Restaurant at the top of the CN tower. An optional post-conference tour to Niagara Falls will also be available. We...
nmrlearner
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04-06-2011 11:00 PM
International Conference on Structural Genomics 2011
International Conference on Structural Genomics 2011
Dear Colleagues,
We are pleased to announce that registration is now open for the International Conference on Structural Genomics 2011, which will be held in Toronto, Canada on May 10-14, 2011. This meeting is the 6th in this series of biennial meetings of the International Structural Genomics Organization. The meeting is designed to serve as a forum to discuss the most recent developments in structural genomics, structural/chemical biology, and their impact on research in biology, medicine and disease. A substantial number of short...
nmrlearner
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11-27-2010 07:34 AM
[NMR paper] Structural genomics and the metabolome: combining computational and NMR methods to id
Structural genomics and the metabolome: combining computational and NMR methods to identify target ligands.
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Curr Opin Drug Discov Devel. 2004 Jan;7(1):62-8
Authors: Parsons L, Orban J
One of the goals of structural genomics is to use three-dimensional structures to gain insights into the function of poorly understood or hypothetical proteins. Approximate functions are often apparent from the protein fold, but more...
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11-24-2010 09:25 PM
[NMR paper] NMR and structural genomics.
NMR and structural genomics.
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Acc Chem Res. 2003 Mar;36(3):207-14
Authors: Staunton D, Owen J, Campbell ID
The role of NMR in structural genomics is outlined, with particular emphasis on using protein domains as targets. Strategies for domain expression, characterization, and labeling are presented.
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11-24-2010 09:01 PM
[NMR paper] Residual dipolar couplings: synergy between NMR and structural genomics.
Residual dipolar couplings: synergy between NMR and structural genomics.
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J Biomol NMR. 2002 Jan;22(1):1-8
Authors: Al-Hashimi HM, Patel DJ
Structural genomics is on a quest for the structure and function of a significant fraction of gene products. Current efforts are focusing on structure determination of single-domain proteins, which can readily be targeted by X-ray crystallography, NMR spectroscopy and computational homology modeling. However,...
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11-24-2010 08:49 PM
[NMR paper] An efficient high-throughput resonance assignment procedure for structural genomics a
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Biochemistry. 2001 Dec 11;40(49):14727-35
Authors: Bhavesh NS, Panchal SC, Hosur RV
Sequence specific resonance assignment is the primary requirement for all investigations of proteins by NMR methods. In the present postgenomic era where structural genomics and protein folding have...
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11-19-2010 08:44 PM
[NMR paper] Protein NMR spectroscopy in structural genomics.
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Nat Struct Biol. 2000 Nov;7 Suppl:982-5
Authors: Montelione GT, Zheng D, Huang YJ, Gunsalus KC, Szyperski T
Protein NMR spectroscopy provides an important complement to X-ray crystallography for structural genomics, both for determining three-dimensional protein structures and in characterizing their biochemical and biophysical functions.
What is Structural Genomics? - News-Medical.net
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