[NMR paper] In-Cell NMR in Human Cells: Direct Protein Expression Allows Structural Studies of Protein Folding and Maturation.
In-Cell NMR in Human Cells: Direct Protein Expression Allows Structural Studies of Protein Folding and Maturation.
In-Cell NMR in Human Cells: Direct Protein Expression Allows Structural Studies of Protein Folding and Maturation.
Acc Chem Res. 2018 Jun 05;:
Authors: Luchinat E, Banci L
Abstract
Cellular structural biology methods are needed to characterize biological processes at atomic resolution in the physiological environment of the cell. Toward this goal, solution in-cell NMR is a powerful approach because it provides...
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06-06-2018 01:42 PM
'Rheostat' identified that helps regulate cell death versus survival decisions - Phys.Org
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Phys.Org
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'Rheostat' identified that helps regulate cell death versus survival decisions
Phys.Org
Researchers used nuclear magnetic resonance (NMR) spectroscopy and other tests to determine how modification of the protein's IDR influenced cell survival. For example, investigators reported that "adjusting" an amino acid in the intrinsically ...
'Rheostat' identified that helps regulate cell death versus survival...
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03-06-2018 03:20 PM
MIT researchers gain new insight on how flu spreads from cell to cell in the body - The Boston Globe
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The Boston Globe
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MIT researchers gain new insight on how flu spreads from cell to cell in the body
The Boston Globe
Cholesterol molecules (green) binding to M2 influenza protein molecules (grey and purple). The shaded grey shapes represent what the configuration looks like on the surface. By Alyssa Meyers Globe Correspondent November 20, 2017. MIT researchers say ...
Cholesterol helps flu virus escape through host cell's...
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11-22-2017 02:01 PM
[NMR paper] Direct structural evidence of protein redox regulation obtained by in-cell NMR.
Direct structural evidence of protein redox regulation obtained by in-cell NMR.
Direct structural evidence of protein redox regulation obtained by in-cell NMR.
Biochim Biophys Acta. 2015 Nov 14;
Authors: Mercatelli E, Barbieri L, Luchinat E, Banci L
Abstract
The redox properties of cellular environments are critical to many functional processes, and are strictly controlled in all living organisms. The glutathione-glutathione disulfide (GSH-GSSG) couple is the most abundant intracellular redox couple. A GSH redox potential can be...
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11-22-2015 03:54 PM
Direct structural evidence of protein redox regulation obtained by in-cell NMR
Direct structural evidence of protein redox regulation obtained by in-cell NMR
Publication date: Available online 14 November 2015
Source:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research</br>
Author(s): Eleonora Mercatelli, Letizia Barbieri, Enrico Luchinat, Lucia Banci</br>
The redox properties of cellular environments are critical to many functional processes, and are strictly controlled in all living organisms. The glutathione-glutathione disulfide (GSH-GSSG) couple is the most abundant intracellular redox couple. A GSH redox potential can be...
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11-17-2015 02:57 PM
Researchers uncover new mechanism that p53 protein uses to trigger cell death - News-Medical.net
Researchers uncover new mechanism that p53 protein uses to trigger cell death - News-Medical.net
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Researchers uncover new mechanism that p53 protein uses to trigger cell death
News-Medical.net
Researchers have identified a new mechanism that the tumor suppressor protein p53 uses to trigger cell death via apoptosis and have shown how the process could be harnessed to kill cancer cells. St. Jude Children's Research Hospital scientists led the ...
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