How Common ALS Mutation Damages Cells and Leads to Toxic Protein Being Produced Detailed in Study - ALS News Today
How Common ALS Mutation Damages Cells and Leads to Toxic Protein Being Produced Detailed in Study - ALS News Today
How Common ALS Mutation Damages Cells and Leads to Toxic Protein Being Produced Detailed in Study ALS News TodayRepeat expansion in the C9orf72 gene, a known ALS mutation, was foun in a lab study to change the length of proteins called DPRs, turning them toxic.
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04-15-2019 07:29 PM
[NMR paper] Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers.
Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers.
Related Articles Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers.
Biomol NMR Assign. 2018 May 21;:
Authors: Patel JR, Xu Y, Capitini C, Chiti F, De Simone A
Abstract
The HypF protein is involved in the maturation and regulation of hydrogenases. The N-terminal domain of HypF (HypF-N) has served as a key model system to study the pathways of protein amyloid formation and the nature of the...
nmrlearner
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05-24-2018 12:57 AM
[NMR paper] NMR metabolomics reveals metabolism-mediated protective effects in liver (HepG2) cells exposed to sub-toxic levels of silver nanoparticles.
NMR metabolomics reveals metabolism-mediated protective effects in liver (HepG2) cells exposed to sub-toxic levels of silver nanoparticles.
NMR metabolomics reveals metabolism-mediated protective effects in liver (HepG2) cells exposed to sub-toxic levels of silver nanoparticles.
J Proteome Res. 2018 Mar 02;:
Authors: Carrola J, Pinto RJB, Nasirpour M, Freire CSR, Gil AM, Santos C, Oliveira H, Duarte IF
Abstract
The expansion of biomedical and therapeutic applications of silver nanoparticles (AgNPs) raises the need to further...
nmrlearner
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03-03-2018 12:01 PM
Parkinson's disease: How toxic proteins damage healthy brain cells - Medical News Today
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Medical News Today
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Parkinson's disease: How toxic proteins damage healthy brain cells
Medical News Today
Scientists have gained insights into how toxic proteins disrupt healthy cell membranes in a process that leads to brain cell death in Parkinson's disease.
Researchers explore how toxic protein clusters linked to Parkinson's ...Brinkwire (press release)
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nmrlearner
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12-18-2017 11:19 PM
Study shows how mutations disrupt ALS-linked protein - Science Codex
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Study shows how mutations disrupt ALS-linked protein
Science Codex
Using nuclear magnetic resonance, computer simulations and microscopy, Fawzi, Brown graduate student Alexander Conicella and colleagues at Lehigh University were able to show that under normal circumstances, TDP-43 molecules concentrate into little ...
Study shows how mutations disrupt ALS-linked protein - Science Codex
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nmrlearner
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08-19-2016 05:49 PM
Assessing the biosimilarity of protein drugs: New study shows method's precision - Phys.Org
Assessing the biosimilarity of protein drugs: New study shows method's precision - Phys.Org
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Phys.Org
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Assessing the biosimilarity of protein drugs: New study shows method's precision
Phys.Org
Monoclonal antibodies are the largest class of approved protein therapeutics in the world, and the ability to extend 2D-NMR methods to this class of therapeutic would represent an important landmark in their analytical...