Study finding could shed light on molecular mechanisms underlying Huntington's disease - News-Medical.net

		BioNMR > NMR community > Online News
Study finding could shed light on molecular mechanisms underlying Huntington's disease - News-Medical.net

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

02-04-2016, 11:46 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,778

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Study finding could shed light on molecular mechanisms underlying Huntington's disease - News-Medical.net

Science World Report

Study finding could shed light on molecular mechanisms underlying Huntington's disease
News-Medical.net
... the process," he said. "Using advanced nuclear magnetic resonance spectroscopy, we were able to provide an unprecedented view of the internal structure of the protein clumps that form in the disease, which we hope will one day lead to new therapies ...
Researchers Describe Brain Plaques Involved In Huntington's DiseaseScience World Report

all 2 news articles »

Study finding could shed light on molecular mechanisms underlying Huntington's disease - News-Medical.net
More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Structure of brain plaques in Huntington's disease described by Pitt team University of Pittsburgh Schools of the ... - EurekAlert (press release) <img alt="" height="1" width="1"> Structure of brain plaques in Huntington's disease described by Pitt team University of Pittsburgh Schools of the ... EurekAlert (press release) "Using advanced nuclear magnetic resonance spectroscopy, we were able to provide an unprecedented view of the internal structure of the protein clumps that form in the disease, which we hope will one day lead to new therapies." The gene associated with ... and more » Structure of brain plaques in Huntington's disease described by Pitt team University of Pittsburgh Schools of the ... - EurekAlert (press...	nmrlearner	Online News	0	02-03-2016 10:22 PM
Study reveals molecular function of protein essential for replication of H5N1 ... - News-Medical.net Study reveals molecular function of protein essential for replication of H5N1 ... - News-Medical.net http://www.bionmr.com//t1.gstatic.com/images?q=tbn:ANd9GcQqQVkN2sOlkhvYowf7yXaO0RlhCYQZ_9zOSx7m7tG2kLZe9aCik1IvkvJcZVU-_BYhJS__lMZX News-Medical.net <img alt="" height="1" width="1"> Study reveals molecular function of protein essential for replication of H5N1 ... News-Medical.net An international collaboration of scientists from the CEA, CNRS, University Joseph Fourier, the EMBL and the ILL has revealed the molecular function of a protein essential for replication of H5N1 influenza...	nmrlearner	Online News	0	12-10-2015 05:49 PM
NDSU assistant professor receives NIH grant to study regulation of ... - News-Medical.net <img alt="" height="1" width="1"> NDSU assistant professor receives NIH grant to study regulation of ... News-Medical.net His laboratory utilizes X-ray crystallography, high-resolution protein nuclear magnetic resonance spectroscopy and small-angle X-ray scattering to determine the atomic resolution structures of proteins, in addition to biophysical and biochemical ... NDSU assistant professor receives NIH grant to study regulation of ... - News-Medical.net More...	nmrlearner	Online News	0	07-20-2015 09:49 AM
Using NMR to study protein motion: an interview with Fabien Ferrage, Ã?cole ... - News-Medical.net Using NMR to study protein motion: an interview with Fabien Ferrage, Ã?cole ... - News-Medical.net <img alt="" height="1" width="1" /> Using NMR to study protein motion: an interview with Fabien Ferrage, Ã?cole ... News-Medical.net We have first applied the new technique to a model protein ubiquitin, which has been studied by NMR for 20 to 25 years and been very well characterized by various methods, including its structure and motions. What we have seen using this apparatus to ... and more » Read here	nmrlearner	Online News	0	08-19-2014 11:21 AM
Study could lead to better understanding of how Notch protein directs healthy ... - News-Medical.net Study could lead to better understanding of how Notch protein directs healthy ... - News-Medical.net <img alt="" height="1" width="1" /> Study could lead to better understanding of how Notch protein directs healthy ... News-Medical.net Johns Hopkins researchers report they have figured out how the aptly named protein Botch blocks the signaling protein called Notch, which helps regulate development. In a report on the discovery, to appear online April 24 in the journal Cell Reports ... Read here	nmrlearner	Online News	0	05-25-2014 06:31 PM
How does the 'kissing disease' replicate itself? - Medical News Today <img alt="" height="1" width="1" /> How does the 'kissing disease' replicate itself? Medical News Today To investigate further, he and his team used innovative nuclear magnetic resonance (NMR) techniques to study how the EBNA2 protein of EBV binds to a protein of the TFIIH complex, which helps regulate a protein called RNA polymerase II. RNA polymerase ... and more » How does the 'kissing disease' replicate itself? - Medical News Today More...	nmrlearner	Online News	0	04-11-2014 02:51 PM
Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease - News-Medical.net Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease - News-Medical.net <img alt="" height="1" width="1" /> Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease News-Medical.net Kai Schlepckow and Harald Schwalbe at the Goethe University Frankfurt am Main have successfully used time-resolved NMR spectroscopic studies to follow what is happening to every individual amino acid as the prion protein molecules aggregateâ??an ... Read here	nmrlearner	Online News	0	08-16-2013 08:36 PM
[NMR paper] Volumetric properties underlying ligand binding in a monomeric hemoglobin: A high-pressure NMR study. Volumetric properties underlying ligand binding in a monomeric hemoglobin: A high-pressure NMR study. Related Articles Volumetric properties underlying ligand binding in a monomeric hemoglobin: A high-pressure NMR study. Biochim Biophys Acta. 2013 Apr 22; Authors: Dellarole M, Roumestand C, Royer C, Lecomte JT Abstract The 2/2 hemoglobin of the cyanobacterium Synechococcus sp. PCC 7002, GlbN, coordinates the heme iron with two histidines and exists either with a b heme or with a covalently attached heme. The binding of exogenous ligands...	nmrlearner	Journal club	0	04-27-2013 01:56 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off