[NMR paper] The Extended Hadamard Transform: Sensitivity-Enhanced NMR Experiments Among Labile and Non-Labile 1Hs of SARS-CoV-2-derived RNAs
The Extended Hadamard Transform: Sensitivity-Enhanced NMR Experiments Among Labile and Non-Labile 1Hs of SARS-CoV-2-derived RNAs
Hadamard encoded saturation transfer can significantly improve the efficiency of NOE-based NMR correlations from labile protons in proteins, glycans and RNAs, increasing the sensitivity of cross-peaks by an order of magnitude and shortening experimental times by >=100-fold. These schemes, however, fail when tackling correlations within a pool of labile protons -for instance imino-imino correlations in RNAs or amide-amide correlations in proteins. Here we analyze...
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[NMR paper] Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids.
Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.nature.com-images-lo_npg.gif http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/https:--www.nature.com-images-npg_logo.gif Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids.
Nat Commun. 2020 10 21;11(1):5317
Authors: Novakovic M,...
[NMR paper] Relaxation-compensated difference spin diffusion NMR for detecting (13)C- (13)C long-range correlations in proteins and polysaccharides.
Relaxation-compensated difference spin diffusion NMR for detecting (13)C- (13)C long-range correlations in proteins and polysaccharides.
Relaxation-compensated difference spin diffusion NMR for detecting (13)C- (13)C long-range correlations in proteins and polysaccharides.
J Biomol NMR. 2014 Dec 16;
Authors: Wang T, Williams JK, Schmidt-Rohr K, Hong M
Abstract
The measurement of long-range distances remains a challenge in solid-state NMR structure determination of biological macromolecules. In 2D and 3D correlation spectra of...
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Relaxation-compensated difference spin diffusion NMR for detecting 13 Câ?? 13 C long-range correlations in proteins and polysaccharides
Relaxation-compensated difference spin diffusion NMR for detecting 13 Câ?? 13 C long-range correlations in proteins and polysaccharides
Abstract
The measurement of long-range distances remains a challenge in solid-state NMR structure determination of biological macromolecules. In 2D and 3D correlation spectra of uniformly 13C-labeled biomolecules, inter-residue, inter-segmental, and intermolecular 13Câ??13C cross peaks that provide important long-range distance constraints for three-dimensional structures often overlap with short-range cross peaks...
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12-15-2014 03:31 PM
[NMR paper] Accurate ab initio prediction of NMR chemical shifts of nucleic acids and nucleic acids/protein complexes.
Accurate ab initio prediction of NMR chemical shifts of nucleic acids and nucleic acids/protein complexes.
Related Articles Accurate ab initio prediction of NMR chemical shifts of nucleic acids and nucleic acids/protein complexes.
Nucleic Acids Res. 2014 Nov 17;
Authors: Victora A, Möller HM, Exner TE
Abstract
NMR chemical shift predictions based on empirical methods are nowadays indispensable tools during resonance assignment and 3D structure calculation of proteins. However, owing to the very limited statistical data basis,...
Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids - Nature.com
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