Scientists decode dynamics of the largest protein-degrading machine in atomic detail - Phys.Org

		BioNMR > NMR community > Online News
Scientists decode dynamics of the largest protein-degrading machine in atomic detail - Phys.Org

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

03-28-2019, 01:56 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,732

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Scientists decode dynamics of the largest protein-degrading machine in atomic detail - Phys.Org

Scientists decode dynamics of the largest protein-degrading machine in atomic detail Phys.OrgProtein nanomachines made of multiple protein molecules are highly dynamic during their actions on their functional targets, sometime called substrates.

Scientists decode dynamics of the largest protein-degrading machine in atomic detail - Phys.Org
More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Scientists Image Atomic Structure of Critical Protein - Plains Gazette Scientists Image Atomic Structure of Critical Protein - Plains Gazette Scientists Image Atomic Structure of Critical Protein Plains GazetteResearchers found new insights of human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3) by studying its atomic structure at Brigham ... Read here	nmrlearner	Online News	0	03-25-2019 08:37 PM
Computer model may help scientists split up, reassemble proteins on command - Phys.org Computer model may help scientists split up, reassemble proteins on command - Phys.org Computer model may help scientists split up, reassemble proteins on command Phys.orgSplitting up and getting back together is always hard to do, but for proteins, it's almost impossible. Read here	nmrlearner	Online News	0	01-07-2019 05:49 AM
Scientists identify protein that may have existed when life began - Phys.org Scientists identify protein that may have existed when life began - Phys.org Scientists identify protein that may have existed when life began Phys.orgHow did life arise on Earth? Rutgers researchers have found among the first and perhaps only hard evidence that simple protein catalysts—essential for cells, ... Read here	nmrlearner	Online News	0	01-07-2019 05:49 AM
Researchers observe the switching of Ras protein in detail - Phys.Org http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcR2-j8hG-wXw4FHHR9hUz42UDKqH3pPhrwcYu4Q2_IoUD6k21dTcRAcGvef-b-_O_ElGVZq7q9U Phys.Org <img alt="" height="1" width="1"> Researchers observe the switching of Ras protein in detail Phys.Org Ras proteins are molecular switches that decide if and when cells divide inside our bodies. An impairment of their function may result in the formation of a tumour. The process of switching the proteins on and off has been observed in detail by a ... Researchers observe the switching of Ras protein in detail - Phys.Org	nmrlearner	Online News	0	03-21-2018 04:04 PM
Magic-angle-spinning NMR used to probe protein/microtubule assembly at atomic scale - Phys.Org Magic-angle-spinning NMR used to probe protein/microtubule assembly at atomic scale - Phys.Org http://www.bionmr.com//t1.gstatic.com/images?q=tbn:ANd9GcRBtQa7jjiFR1Ka7bIeJtv8GwyoUep-8VjT60fBCPfstugvxkbxBGj14wdtmcsu0NjpeAQ5zKru Phys.Org <img alt="" height="1" width="1"> Magic-angle-spinning NMR used to probe protein/microtubule assembly at atomic scale Phys.Org "Just as we are always moving our arms and legs about, proteins are very dynamic. They do not stand still," Polenova says. "These motions are essential to their biological function, and NMR spectroscopy is the only technique...	nmrlearner	Online News	0	12-02-2017 02:54 PM
Researchers probe brain disease-causing proteins at the atomic level - Phys.Org Researchers probe brain disease-causing proteins at the atomic level - Phys.Org http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcS-sN8485QvvUQ7Ff6vlVsVUtDn1pu0wAR_CUmuY3TdtC1SeUpFv59P1zO7uMBFSwLRIoFzw0li Phys.Org <img alt="" height="1" width="1"> Researchers probe brain disease-causing proteins at the atomic level Phys.Org Key interresidue contacts and schematic model of the human PrP23-144 amyloid Î²-core. a Small regions of a 900 MHz two-dimensional 13Câ??13C DARR solid-state NMR spectrum recorded with a mixing time of 500 ms for amyloid fibrils generated from ... and...	nmrlearner	Online News	0	11-06-2017 05:23 PM
MRI machine at the nanoscale breaks world records - Phys.Org http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcTABLBplX61Dvn-QX6tX4bLjUpSlVti6W1TgqOcaJoEylwFjKpPgGelr2Eb27zALg88A--RycSz Phys.Org <img alt="" height="1" width="1"> MRI machine at the nanoscale breaks world records Phys.Org A new nuclear magnetic resonance (NMR) microscope gives researchers an improved instrument to study fundamental physical processes. It also offers new possibilities for medical scienceâ??for example, to better study proteins in Alzheimer's patients' brains. MRI machine at the nanoscale breaks world records - Phys.Org	nmrlearner	Online News	0	07-16-2016 04:54 AM
Magic-angle-spinning NMR used to probe protein/microtubule assembly at atomic ... - Phys.Org Magic-angle-spinning NMR used to probe protein/microtubule assembly at atomic ... - Phys.Org http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcT9L3q8W70RahhoVW6p4h_H8hwG5OrsBRguWtW3kPiqT8wa-znuPREK74WT8UVXzeFKbRdUurxU Phys.Org <img alt="" height="1" width="1"> Magic-angle-spinning NMR used to probe protein/microtubule assembly at atomic ... Phys.Org The research team used magic-angle-spinning nuclear magnetic resonance spectrometry (NMR) in the Department of Chemistry and Biochemistry at UD to unveil the structure of the CAP-Gly protein assembled on polymerized microtubules....	nmrlearner	Online News	0	11-26-2015 12:13 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off