Revealing structural secrets of a key cancer protein - EurekAlert

		BioNMR > NMR community > Online News
Revealing structural secrets of a key cancer protein - EurekAlert

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

10-19-2023, 01:17 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,778

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Revealing structural secrets of a key cancer protein - EurekAlert

Revealing structural secrets of a key cancer protein - EurekAlert

Revealing structural secrets of a key cancer protein EurekAlert Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Elusive cancer-related protein captured in flight - EurekAlert Elusive cancer-related protein captured in flight - EurekAlert Elusive cancer-related protein captured in flight EurekAlert Read here	nmrlearner	Online News	0	03-21-2020 12:53 AM
The genome guardian turns to the dark side: Opportunity for drug discovery against cancer? - EurekAlert (press release) http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcSTU36-wxqtoiw-MVyMJ8jZIsZronyd3XLuqFQlFSh2MJ5zMwQASWuk1sSwVN0zcp24jWvS2R49 EurekAlert (press release) <img alt="" height="1" width="1"> The genome guardian turns to the dark side: Opportunity for drug discovery against cancer? EurekAlert (press release) ... diesel combustion, among many others), in the lab the research group applied different concentrations of chemicals and/or high hydrostatic pressure to disrupt the equilibrium of native proteins, as detected by fluorescence and Nuclear Magnetic ... The genome guardian...	nmrlearner	Online News	0	05-31-2018 11:07 PM
Enzyme's movement may be key to new cancer drugs - EurekAlert (press release) http://www.bionmr.com//t1.gstatic.com/images?q=tbn:ANd9GcTsNtH9YpxxAQ6ksPtPSZU0Z09vvbZhDQEOKHaJ3v7FZ4YWTEIyvhvW3H5toO9Rh1H0x8fgcCvA EurekAlert (press release) <img alt="" height="1" width="1"> Enzyme's movement may be key to new cancer drugs EurekAlert (press release) To watch a kinase called mitogen-activated protein kinase (MAPK) p38 in action, the researchers used nuclear magnetic resonance (NMR) spectroscopy. All necessary molecules had to bind to p38 for the enzyme to become active. Only then could the ... Enzyme's movement may be key to new cancer drugs - EurekAlert (press...	nmrlearner	Online News	0	05-15-2018 03:38 PM
Study shows how mutations disrupt ALS-linked protein \| EurekAlert ... - EurekAlert (press release) http://www.bionmr.com//t3.gstatic.com/images?q=tbn:ANd9GcSO0MkkUxtPQ4lK58RIiZ3I6PBDLS0IC8TOKFk2eGEQsEQ7UT3TJT4nSpwXD4xz1LnsOr5T6RU5 EurekAlert (press release) <img alt="" height="1" width="1"> Study shows how mutations disrupt ALS-linked protein \| EurekAlert ... EurekAlert (press release) Structural biologists provide a new explanation for how ALS-associated genetic flaws interfere with the proper function and behavior of the protein TDP-43. and more » Study shows how mutations disrupt ALS-linked protein \| EurekAlert ... - EurekAlert (press release)	nmrlearner	Online News	0	08-19-2016 04:05 AM
[NMR paper] Solution NMR structures of immunoglobulin-like domains 7 and 12 from obscurin-like protein 1 contribute to the structural coverage of the human cancer protein interaction network. Solution NMR structures of immunoglobulin-like domains 7 and 12 from obscurin-like protein 1 contribute to the structural coverage of the human cancer protein interaction network. Related Articles Solution NMR structures of immunoglobulin-like domains 7 and 12 from obscurin-like protein 1 contribute to the structural coverage of the human cancer protein interaction network. J Struct Funct Genomics. 2014 Jul 3; Authors: Pulavarti SV, Huang YJ, Pederson K, Acton TB, Xiao R, Everett JK, Prestegard JH, Montelione GT, Szyperski T Abstract ...	nmrlearner	Journal club	0	07-06-2014 08:28 PM
Structure of bacterial nanowire protein hints at secrets of conduction - HealthCanal.com Structure of bacterial nanowire protein hints at secrets of conduction - HealthCanal.com <img alt="" height="1" width="1" /> Structure of bacterial nanowire protein hints at secrets of conduction HealthCanal.com But the protein by itself isn't enough to reveal how conduction works. Many pilin proteins work together to form a fiber, and Reardon and Mueller only had one. Nor did the researchers have the whole fiber to put into the NMR instrument. To get more ... Read here	nmrlearner	Online News	0	11-25-2013 11:32 AM
Structure of bacterial nanowire protein hints at secrets of conduction - Space Daily Structure of bacterial nanowire protein hints at secrets of conduction - Space Daily <img alt="" height="1" width="1" /> Structure of bacterial nanowire protein hints at secrets of conduction Space Daily But the protein by itself isn't enough to reveal how conduction works. Many pilin proteins work together to form a fiber, and Reardon and Mueller only had one. Nor did the researchers have the whole fiber to put into the NMR instrument. To get more ... Read here	nmrlearner	Online News	0	11-19-2013 11:35 AM
NMR Structural Biology and Biophysics of Protein:Protein Complexes, National Cancer Institute, Frederick, MD, United States NMR Structural Biology and Biophysics of Protein:Protein Complexes, National Cancer Institute, Frederick, MD, United States Postdoctoral positions are available in the Macromolecular NMR section of the Structural Biophysics Laboratory headed by Dr. R. Andrew Byrd at the National Cancer Institute. The Byrd lab combines NMR structural biology & Small Angle Xray Scattering (... More...	nmrlearner	Job marketplace	0	11-15-2011 11:36 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off