Researchers uncover how small heat shock protein interacts with other proteins - News-Medical.net

		BioNMR > NMR community > Online News
Researchers uncover how small heat shock protein interacts with other proteins - News-Medical.net

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

10-16-2015, 12:49 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,732

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Researchers uncover how small heat shock protein interacts with other proteins - News-Medical.net

Researchers uncover how small heat shock protein interacts with other proteins - News-Medical.net

Researchers uncover how small heat shock protein interacts with other proteins
News-Medical.net
... in uncovering precisely this mechanism. Using a refined procedure of solid-state nuclear magnetic resonance spectroscopy (solid-state NMR), they managed, for the first time ever, to identify the sites in the alpha-B-crystallin that attach to the ...

and more »
Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Small Heat Shock Protein As Model for Alzheimer Medication - Scicasts (press release) (blog) Small Heat Shock Protein As Model for Alzheimer Medication - Scicasts (press release) (blog) http://www.bionmr.com//t1.gstatic.com/images?q=tbn:ANd9GcQ9moy7bI6-CN006Z0Ht_YPEwpfVDX7qETMgRnwpztgVdqHvywdHobvblWhtaMWJLlFb1Qq4Dw Scicasts (press release) (blog) <img alt="" height="1" width="1"> Small Heat Shock Protein As Model for Alzheimer Medication Scicasts (press release) (blog) As Reif and his colleagues have discovered, it binds protein types that, unlike the beta-amyloid, clump together in an unordered manner. The researchers will be supported by the new NMR Center that is currently...	nmrlearner	Online News	0	10-14-2015 12:47 PM
New Alzheimer's treatments may arise from modeling 'heat shock proteins' - Medical News Today New Alzheimer's treatments may arise from modeling 'heat shock proteins' - Medical News Today http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcSJynzcKblVeZYmd6Hg316eXCekMeseTFC-l6eQ1GijAxT4CVL48l8lLOo8lTJenbQdHBn1vnKn Medical News Today <img alt="" height="1" width="1"> New Alzheimer's treatments may arise from modeling 'heat shock proteins' Medical News Today Using solid-state nuclear magnetic resonance (NMR) spectroscopy, the researchers identified the exact sites in the alpha-B-crystallin structure that attach to the beta-amyloid. The achievement is the result of...	nmrlearner	Online News	0	10-13-2015 06:03 PM
Small heat shock protein as model for Alzheimer's medication - News-Medical.net Small heat shock protein as model for Alzheimer's medication - News-Medical.net http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcSs_jrKR5ICaGu4iH3hpUBJnSF5w-iMfF0Qy_VGXVCtMo1BC7oe7a7d_oQiN2r1yXeRz2_shIs News-Medical.net <img alt="" height="1" width="1"> Small heat shock protein as model for Alzheimer's medication News-Medical.net Using a refined procedure of solid-state nuclear magnetic resonance spectroscopy (solid-state NMR), they managed, for the first time ever, to identify the sites in the alpha-B-crystallin that attach to the beta-amyloid. It is the first direct...	nmrlearner	Online News	0	10-13-2015 05:51 AM
Researchers uncover new mechanism that p53 protein uses to trigger cell death - News-Medical.net Researchers uncover new mechanism that p53 protein uses to trigger cell death - News-Medical.net <img alt="" height="1" width="1"> Researchers uncover new mechanism that p53 protein uses to trigger cell death News-Medical.net Researchers have identified a new mechanism that the tumor suppressor protein p53 uses to trigger cell death via apoptosis and have shown how the process could be harnessed to kill cancer cells. St. Jude Children's Research Hospital scientists led the ... and more » Read here	nmrlearner	Online News	0	07-31-2015 07:53 PM
Researchers find new method to measure modified protein structures in ... - News-Medical.net <img alt="" height="1" width="1" /> Researchers find new method to measure modified protein structures in ... News-Medical.net Although there is a series of techniques to study structurally modified proteins, such as x-ray crystallography, nuclear magnetic resonance spectroscopy and other spectroscopic techniques, they cannot be used to analyse complex biological samples. Researchers find new method to measure modified protein structures in ... - News-Medical.net More...	nmrlearner	Online News	0	09-16-2014 08:38 PM
Researchers solve complete 3-D structure of E6 proteins in HPV 16 - News-Medical.net Researchers solve complete 3-D structure of E6 proteins in HPV 16 - News-Medical.net <img alt="" height="1" width="1" /> Researchers solve complete 3-D structure of E6 proteins in HPV 16 News-Medical.net Success depended on two factors: the development of methods for isolating protein E6 as well as the use of nuclear magnetic resonance (NMR) and crystallography techniques. Having dealt with various aggregation and purification problems, the researchers ... and more » Read here	nmrlearner	Online News	0	02-16-2013 05:53 AM
Scientists uncover small molecules that may prevent ebola infection : Study - Medical Daily <img alt="" height="1" width="1" /> Scientists uncover small molecules that may prevent ebola infection : Study Medical Daily Exactly how and where these small molecules bind to the virus's protein coat is now being determined through nuclear magnetic resonance spectroscopy, ... Scientists uncover small molecules that may prevent ebola infection : Study - Medical Daily More...	nmrlearner	Online News	0	01-26-2011 04:27 PM
Purifying Proteins: Researchers Use NMR To Improve Drug Development - Medical News To Purifying Proteins: Researchers Use NMR To Improve Drug Development - Medical News Today (press release) <img alt="" height="1" width="1" /> Purifying Proteins: Researchers Use NMR To Improve Drug Development Medical News Today (press release) From the NMR data, they were able to determine what part and type of the protein the ligands were binding to and how strongly they would bind. ... and more » Read here	nmrlearner	Online News	0	10-26-2010 08:48 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off