Researchers probe brain disease-causing proteins at the atomic level: A change in a single amino acid determines which species are vulnerable, study finds - Science Daily

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Researchers probe brain disease-causing proteins at the atomic level: A change in a single amino acid determines which species are vulnerable, study finds - Science Daily

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Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

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GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

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TALOS

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d2D

PECAN

Flexibility from chemical shifts:

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Interactions from chemical shifts:

HADDOCK

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Methyl S2

B-factor

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Chemical shifts prediction:

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Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

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Protein disorder:

DisMeta

Protein solubility:

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04-06-2019, 06:58 PM

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Researchers probe brain disease-causing proteins at the atomic level: A change in a single amino acid determines which species are vulnerable, study finds - Science Daily

Researchers probe brain disease-causing proteins at the atomic level: A change in a single amino acid determines which species are vulnerable, study finds - Science Daily

Researchers probe brain disease-causing proteins at the atomic level: A change in a single amino acid determines which species are vulnerable, study finds Science DailyResearchers studying a protein that causes a hereditary degenerative brain disease in humans have discovered that the human, mouse and hamster forms of ...

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