Researchers Detangle Protein Interaction Implicated in Down Syndrome and Alzheimer's - UANews

		BioNMR > NMR community > Online News
Researchers Detangle Protein Interaction Implicated in Down Syndrome and Alzheimer's - UANews

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

07-29-2020, 05:17 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,777

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Researchers Detangle Protein Interaction Implicated in Down Syndrome and Alzheimer's - UANews

Researchers Detangle Protein Interaction Implicated in Down Syndrome and Alzheimer's - UANews

Researchers Detangle Protein Interaction Implicated in Down Syndrome and Alzheimer's UANews Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Cushing's syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity - Science Advances Cushing's syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity - Science Advances Cushing's syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity Science Advances Read here	nmrlearner	Online News	0	02-29-2020 09:52 PM
[NMR paper] NMR assignments of the WBSCR27 protein related to Williams-Beuren syndrome. NMR assignments of the WBSCR27 protein related to Williams-Beuren syndrome. Related Articles NMR assignments of the WBSCR27 protein related to Williams-Beuren syndrome. Biomol NMR Assign. 2018 Jun 04;: Authors: Mariasina SS, Petrova OA, Osterman IA, Sergeeva OV, Efimov SV, Klochkov VV, Sergiev PV, Dontsova OA, Huang TH, Chang CF, Polshakov VI Abstract Williams-Beuren syndrome is a genetic disorder characterized by physiological and mental abnormalities, and is caused by hemizygous deletion of several genes in chromosome 7. One of...	nmrlearner	Journal club	0	06-06-2018 01:42 PM
Enzyme's Movement May Be Key to New Cancer Drugs - UANews (press release) http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcRU5ps9B_AsxWZutYNhbyuT0iN6r4CcMTrYGFNoboImA6hS0X4DCbMdeGnZUmDxRuSxqCaImqyS UANews (press release) <img alt="" height="1" width="1"> Enzyme's Movement May Be Key to New Cancer Drugs UANews (press release) To watch a kinase called mitogen-activated protein kinase (MAPK) p38 in action, the researchers used nuclear magnetic resonance (NMR) spectroscopy. All necessary molecules had to bind to p38 for the enzyme to become active. Only then could the ... Enzyme's Movement May Be Key to New Cancer Drugs - UANews (press release)	nmrlearner	Online News	0	05-16-2018 03:41 AM
Researchers focus on cell membranes to develop Alzheimer's ... - Science Daily http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcSk9DVaZBLNsHjBmTDgD4gJ20XgNllBuUlwlEtJR8kEpr08gPCB6x7xum3zJSyo2GIakkMUgjxV ReliaWire <img alt="" height="1" width="1"> Researchers focus on cell membranes to develop Alzheimer's ... Science Daily Thin parts of the cell membranes of neurons turn out to be particularly vulnerable to a protein that collects in the brain of people with Alzheimer's disease, ... Thinner Neuronal Membranes Provide Amyloid-beta Access PointsReliaWire all 2 news articles »	nmrlearner	Online News	0	03-26-2017 11:10 PM
Researchers find clue to stopping Alzheimer's-like diseases - HealthCanal.com <img alt="" height="1" width="1" /> Researchers find clue to stopping Alzheimer's-like diseases HealthCanal.com The study used Nuclear Magnetic Resonance spectroscopy to look at a molecular level at the interactions of the different proteins and identified tiny differences in the physical and chemical properties of the surfaces that made a great difference to ... and more » Researchers find clue to stopping Alzheimer's-like diseases - HealthCanal.com More...	nmrlearner	Online News	0	06-27-2014 11:12 PM
[NMR paper] NMR assignments of the winged-helix domain of human werner syndrome protein. NMR assignments of the winged-helix domain of human werner syndrome protein. Related Articles NMR assignments of the winged-helix domain of human werner syndrome protein. J Biomol NMR. 2005 Jul;32(3):261 Authors: Sun JZ, Feng HQ, Lin GX, Zeng W, Hu JS	nmrlearner	Journal club	0	12-01-2010 06:56 PM
[NMR paper] High precision NMR structure of YhhP, a novel Escherichia coli protein implicated in High precision NMR structure of YhhP, a novel Escherichia coli protein implicated in cell division. Related Articles High precision NMR structure of YhhP, a novel Escherichia coli protein implicated in cell division. J Mol Biol. 2000 Nov 24;304(2):219-29 Authors: Katoh E, Hatta T, Shindo H, Ishii Y, Yamada H, Mizuno T, Yamazaki T YhhP, a small protein of 81 amino acid residues encoded by the yhhP gene in the Escherichia coli database, is implicated in cell division although the precise biological function of this protein has not been yet...	nmrlearner	Journal club	0	11-19-2010 08:29 PM
[NMR paper] Interaction of synthetic Alzheimer beta-protein-derived analogs with aqueous aluminum Interaction of synthetic Alzheimer beta-protein-derived analogs with aqueous aluminum: a low-field 27Al NMR investigation. Related Articles Interaction of synthetic Alzheimer beta-protein-derived analogs with aqueous aluminum: a low-field 27Al NMR investigation. J Protein Chem. 1995 Nov;14(8):633-44 Authors: Vyas SB, Duffy LK Synthetic peptides corresponding to the soluble Alzheimer beta-protein, i.e., beta 1-40 and beta 6-25, were utilized to investigate the association of aluminum using low-field 27Al nuclear magnetic resonance (NMR)...	nmrlearner	Journal club	0	08-22-2010 03:50 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off