Protein Research Could Lead to New Drugs for ALS - R & D Magazine

		BioNMR > NMR community > Online News
Protein Research Could Lead to New Drugs for ALS - R & D Magazine

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

01-19-2018, 08:57 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,777

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Protein Research Could Lead to New Drugs for ALS - R & D Magazine

R & D Magazine

Protein Research Could Lead to New Drugs for ALS
R & D Magazine
The researchers examined hnRNPA2, a protein that is mutated in disease and collects in membrane-less organelles, where they may use their low-complexity domain to stick together. The researchers used nuclear magnetic resonance spectroscopy, computer ...
Proteomics Finding May Lead to Therapy Targeted at Cellular Pathway Linked to ALSGenetic Engineering & Biotechnology News

all 3 news articles »

Protein Research Could Lead to New Drugs for ALS - R & D Magazine
More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Finishing the Jigsaw: Identifying How Drugs Interact with Molecules Could Lead to Better Treatments - Technology Networks http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcS7PYk1K-w2WhKK0ifa6MHwKb1uYMaslHG58R3g7ElJZhDnzULNiJBuYHVkNrsfa3-Zj95RZiWL Technology Networks <img alt="" height="1" width="1"> Finishing the Jigsaw: Identifying How Drugs Interact with Molecules Could Lead to Better Treatments Technology Networks It adapts a technique known as ligand-based Nuclear Magnetic Resonance (NMR) spectroscopy to reveal which amino acids in the protein are involved in binding to the drug. They were able to do this by examining the drug and without having to label the ... Finishing the Jigsaw:...	nmrlearner	Online News	0	10-09-2017 04:12 PM
[NMR paper] Inhibition of Protein–Protein Interactions: New Options for Developing Drugs against Neglected Tropical Diseases Inhibition of Protein–Protein Interactions: New Options for Developing Drugs against Neglected Tropical Diseases Wake up! Sleeping sickness and Chagas disease are neglected tropical diseases caused by trypanosome infections. Small molecules that disrupt a crucial protein–protein interaction in the parasites offer a new approach to drug development for these diseases. More...	nmrlearner	Journal club	0	08-07-2017 06:41 AM
Research May Lead to New Drugs for Heart Disease, Other Ailments - Exchange Morning Post (press release) <img alt="" height="1" width="1" /> Research May Lead to New Drugs for Heart Disease, Other Ailments Exchange Morning Post (press release) The U of G team has demonstrated a new way of looking at structures of cell membrane proteins using solid-state nuclear magnetic resonance (NMR) spectroscopy. NMR shows molecular structure by detecting magnetic spins and interactions of atomic nuclei ... Research May Lead to New Drugs for Heart Disease, Other Ailments - Exchange Morning Post (press release) More...	nmrlearner	Online News	0	09-10-2013 08:44 PM
Research May Lead to New Drugs for Heart Disease, Other Ailments - HealthCanal.com <img alt="" height="1" width="1" /> Research May Lead to New Drugs for Heart Disease, Other Ailments HealthCanal.com The U of G team has demonstrated a new way of looking at structures of cell membrane proteins using solid-state nuclear magnetic resonance (NMR) spectroscopy. NMR shows molecular structure by detecting magnetic spins and interactions of atomic nuclei ... and more » Research May Lead to New Drugs for Heart Disease, Other Ailments - HealthCanal.com More...	nmrlearner	Online News	0	09-10-2013 08:00 AM
Team Effort - R&D Magazine - R & D Magazine http://www.bionmr.com//nt1.ggpht.com/news/tbn/XZPfJpqPu06j9M/6.jpg R & D Magazine <img alt="" height="1" width="1" /> Team Effort - R&D Magazine R & D Magazine To achieve the best understanding of protein structure, researchers often look to nuclear magnetic resonance (NMR) and X-ray diffraction (XRD) techniques. High-powered X-rays have led to a host of fundamental discoveries in biology. However, the ... Team Effort - R&D Magazine - R & D Magazine	nmrlearner	Online News	0	04-24-2013 09:48 PM
Insights into protein folding may lead to better flu vaccine - R & D Magazine Insights into protein folding may lead to better flu vaccine - R & D Magazine <img alt="" height="1" width="1" /> Insights into protein folding may lead to better flu vaccine R & D Magazine The method, described online in the Proceedings of the National Academy of Sciences July 16, allows researchers to take snapshots of the cell's protein-making machineryâ??called ribosomesâ??in various stages of protein production. The scientists then ... Read here	nmrlearner	Online News	0	07-27-2012 11:58 AM
Protein pathways provide clues in leukemia research - R & D Magazine Protein pathways provide clues in leukemia research - R & D Magazine <img alt="" height="1" width="1" /> Protein pathways provide clues in leukemia research R & D Magazine If it's possible to know the protein signaling pathways of particular types of leukemia, .... of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. Read here	nmrlearner	Online News	0	06-14-2012 01:45 PM
$1.2M for Biomed Research - Lab Manager Magazine <img alt="" height="1" width="1" /> $1.2M for Biomed Research Lab Manager Magazine NIH also awarded UGA a $363700 grant for a new electronics console for the 800 MHz nuclear magnetic resonance spectrometer housed in the Fred C. Davison Life Sciences Complex. The more reliable console will further research in protein chemistry, ... $1.2M for Biomed Research - Lab Manager Magazine More...	nmrlearner	Online News	0	10-03-2011 08:40 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off