Protein footprinting patent - Scientist Live

		BioNMR > NMR community > Online News
Protein footprinting patent - Scientist Live

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

05-13-2021, 07:58 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,778

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Protein footprinting patent - Scientist Live

Protein footprinting patent Scientist Live
Protein footprinting patent - Scientist Live
More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
GenNext Technologies has announced NIH grant funding of nearly $7M leads to a seminal protein footprinting patent - SelectScience GenNext Technologies has announced NIH grant funding of nearly $7M leads to a seminal protein footprinting patent SelectScience GenNext Technologies has announced NIH grant funding of nearly $7M leads to a seminal protein footprinting patent - SelectScience More...	nmrlearner	Online News	0	04-28-2021 10:16 PM
[NMR paper] Free-Radical Membrane Protein Footprinting by Photolysis of Perfluoroisopropyl Iodide Partitioned to Detergent Micelle by Sonication Free-Radical Membrane Protein Footprinting by Photolysis of Perfluoroisopropyl Iodide Partitioned to Detergent Micelle by Sonication Angewandte Chemie International Edition, EarlyView. More...	nmrlearner	Journal club	0	03-10-2021 04:53 PM
[ASAP] Polyanions Cause Protein Destabilization Similar to That in Live Cells Polyanions Cause Protein Destabilization Similar to That in Live Cells https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.0c00889/20210226/images/medium/bi0c00889_0009.gif Biochemistry DOI: 10.1021/acs.biochem.0c00889 http://feeds.feedburner.com/~r/acs/bichaw/~4/GMUhclWUxd4 More...	nmrlearner	Journal club	0	02-28-2021 06:53 AM
[ASAP] Trifluoroethanol Partially Unfolds G93A SOD1 Leading to Protein Aggregation: A Study by Native Mass Spectrometry and FPOP Protein Footprinting Trifluoroethanol Partially Unfolds G93A SOD1 Leading to Protein Aggregation: A Study by Native Mass Spectrometry and FPOP Protein Footprinting https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.0c00425/20200921/images/medium/bi0c00425_0008.gif Biochemistry DOI: 10.1021/acs.biochem.0c00425 http://feeds.feedburner.com/~r/acs/bichaw/~4/CoL32Spwwvs More...	nmrlearner	Journal club	0	09-24-2020 07:17 PM
Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.7b00874/20171220/images/medium/bi-2017-00874m_0009.gif Biochemistry DOI: 10.1021/acs.biochem.7b00874 http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/bichaw/~4/m9uAQk5ldxQ More...	nmrlearner	Journal club	0	12-20-2017 10:12 PM
[NMR paper] Carbene footprinting reveals binding interfaces of a multimeric membrane spanning protein Carbene footprinting reveals binding interfaces of a multimeric membrane spanning protein Mapping the interaction sites between membrane spanning proteins is a key challenge in structural biology. In this study a carbene footprinting approach is developed and applied to identify the interfacial sites of a trimeric, integral membrane protein, OmpF, solubilised in micelles. The diazirine-based footprinting probe is effectively sequestered by, and incorporated into, the micelles leading to efficient labelling of the membrane-spanning regions of the protein upon irradiation at 349 nm. Areas...	nmrlearner	Journal club	0	09-27-2017 04:26 PM
[NMR paper] Laser-initiated Radical Trifluoromethylation of Peptides and Proteins and Its Application to Mass Spectrometry-Based Protein Footprinting Laser-initiated Radical Trifluoromethylation of Peptides and Proteins and Its Application to Mass Spectrometry-Based Protein Footprinting We describe a novel, laser-initiated radical trifluoromethylation for protein footprinting and establish its broad residue coverage. CF3 reacts with 18 of 20 common amino acids including Gly, Ala, Ser, Thr, Asp, Glu that are relatively "silent" with OH. This new approach to footprinting is a bridge between trifluoromethylation in materials and medicinal chemistry and structural biology and biotechnology. Its application to a membrane protein and to...	nmrlearner	Journal club	0	09-13-2017 08:48 PM
Structural Analysis of the Glycosylated Intact HIV-1 gp120–b12 Antibody Complex Using Hydroxyl Radical Protein Footprinting Structural Analysis of the Glycosylated Intact HIV-1 gp120–b12 Antibody Complex Using Hydroxyl Radical Protein Footprinting http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.6b00888/20170206/images/medium/bi-2016-008884_0009.gif Biochemistry DOI: 10.1021/acs.biochem.6b00888 http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/bichaw/~4/yGaVonLnOfQ More...	nmrlearner	Journal club	0	02-07-2017 04:14 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off