Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution - Science Advances

		BioNMR > NMR community > Online News
Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution - Science Advances

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

07-22-2020, 09:36 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,715

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution - Science Advances

Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution - Science Advances

Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution Science Advances Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples - Science Advances Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples - Science Advances Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples Science Advances Read here	nmrlearner	Online News	0	03-16-2020 04:59 PM
Solvent-dependent segmental dynamics in intrinsically disordered proteins - Science Advances Solvent-dependent segmental dynamics in intrinsically disordered proteins - Science Advances Solvent-dependent segmental dynamics in intrinsically disordered proteins Science Advances Read here	nmrlearner	Online News	0	02-29-2020 09:52 PM
Extending electron paramagnetic resonance to nanoliter volume protein single crystals using a self-resonant microhelix - Science Advances Extending electron paramagnetic resonance to nanoliter volume protein single crystals using a self-resonant microhelix - Science Advances Extending electron paramagnetic resonance to nanoliter volume protein single crystals using a self-resonant microhelix Science Advances Read here	nmrlearner	Online News	0	02-29-2020 09:52 PM
Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins - Science Advances Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins - Science Advances Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins Science AdvancesIn every established species, protein-protein interactions have evolved such that they are fit for purpose. However, the molecular details of the evolution of new ... Read here	nmrlearner	Online News	0	04-25-2019 05:39 PM
Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins - Science Advances Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins - Science Advances Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins Science AdvancesIn every established species, protein-protein interactions have evolved such that they are fit for purpose. However, the molecular details of the evolution of new ... Read here	nmrlearner	Online News	0	01-07-2019 05:49 AM
[NMR paper] Revealing Conformational Variants of Solution-Phase Intrinsically Disordered Tau Protein at the Single-Molecule Level Revealing Conformational Variants of Solution-Phase Intrinsically Disordered Tau Protein at the Single-Molecule Level Intrinsically disordered proteins, such as tau protein, adopt a variety of conformations in solution, complicating solution-phase structural studies. We employ an anti-Brownian electrokinetic (ABEL) trap to prolong measurements of single tau proteins in solution. Once trapped, we record the fluorescence anisotropy to investigate the diversity of conformations sampled by the single molecules. A distribution of anisotropy values obtained from trapped tau protein is...	nmrlearner	Journal club	0	10-24-2017 05:09 PM
[NMR paper] Toward optimal-resolution NMR of intrinsically disordered proteins. Toward optimal-resolution NMR of intrinsically disordered proteins. Related Articles Toward optimal-resolution NMR of intrinsically disordered proteins. J Magn Reson. 2014 Apr;241:41-52 Authors: Nová?ek J, Zídek L, Sklená? V Abstract Proteins, which, in their native conditions, sample a multitude of distinct conformational states characterized by high spatiotemporal heterogeneity, most often termed as intrinsically disordered proteins (IDPs), have become a target of broad interest over the past 15years. With the growing evidence of their...	nmrlearner	Journal club	0	03-25-2014 11:49 AM
Toward optimal-resolution NMR of intrinsically disordered proteins Toward optimal-resolution NMR of intrinsically disordered proteins Publication date: April 2014 Source:Journal of Magnetic Resonance, Volume 241</br> Author(s): Ji?í Nová?ek , Lukáš Žídek , Vladimír Sklená?</br> Proteins, which, in their native conditions, sample a multitude of distinct conformational states characterized by high spatiotemporal heterogeneity, most often termed as intrinsically disordered proteins (IDPs), have become a target of broad interest over the past 15years. With the growing evidence of their important roles in fundamental cellular...	nmrlearner	Journal club	0	03-21-2014 12:52 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off