[NMR paper] Assessment of Prediction Methods for Protein Structures Determined by NMR in CASP14: Impact of AlphaFold2
Assessment of Prediction Methods for Protein Structures Determined by NMR in CASP14: Impact of AlphaFold2
NMR studies can provide unique information about protein conformations in solution. In CASP14, three reference structures provided by solution NMR methods were available (T1027, T1029, and T1055), as well as a fourth data set of NMR-derived contacts for an integral membrane protein (T1088). For the three targets with NMR-based structures, the best prediction results ranged from very good (GDT_TS = 0.90, for T1055) to poor (GDT_TS = 0.47, for T1029). We explored the basis of these...
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[NMR paper] The power, pitfalls and potential of the nanodisc system for NMR-based studies.
The power, pitfalls and potential of the nanodisc system for NMR-based studies.
Related Articles The power, pitfalls and potential of the nanodisc system for NMR-based studies.
Biol Chem. 2016 Jul 23;
Authors: Viegas A, Viennet T, Etzkorn M
Abstract
The choice of a suitable membrane mimicking environment is of fundamental importance for the characterization of structure and function of membrane proteins. In this respect, usage of the lipid bilayer nanodisc technology provides a unique potential for NMR-based studies. This review...
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07-28-2016 12:07 PM
[NMR paper] Contact model for the prediction of NMR N-H order parameters in globular proteins.
Contact model for the prediction of NMR N-H order parameters in globular proteins.
Related Articles Contact model for the prediction of NMR N-H order parameters in globular proteins.
J Am Chem Soc. 2002 Oct 30;124(43):12654-5
Authors: Zhang F, Brüschweiler R
An analytical relationship is presented for the estimation of NMR S2 order parameters of N-HN vectors of the protein backbone from high-resolution protein structures. The relationship solely depends on close contacts of the peptide plane to the rest of the protein. Application of the...
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11-24-2010 08:58 PM
[NMR paper] The structure and dipole moment of globular proteins in solution and crystalline stat
The structure and dipole moment of globular proteins in solution and crystalline states: use of NMR and X-ray databases for the numerical calculation of dipole moment.
Related Articles The structure and dipole moment of globular proteins in solution and crystalline states: use of NMR and X-ray databases for the numerical calculation of dipole moment.
Biopolymers. 2001 Apr 5;58(4):398-409
Authors: Takashima S
The large dipole moment of globular proteins has been well known because of the detailed studies using dielectric relaxation and...
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11-19-2010 08:32 PM
[NMR paper] HYDRONMR: prediction of NMR relaxation of globular proteins from atomic-level structu
HYDRONMR: prediction of NMR relaxation of globular proteins from atomic-level structures and hydrodynamic calculations.
Related Articles HYDRONMR: prediction of NMR relaxation of globular proteins from atomic-level structures and hydrodynamic calculations.
J Magn Reson. 2000 Nov;147(1):138-46
Authors: García de la Torre J, Huertas ML, Carrasco B
The heteronuclear NMR relaxation of globular proteins depends on the anisotropic rotational diffusion tensor. Using our previous developments for prediction of hydrodynamic properties of arbitrarily...
The power and pitfalls of AlphaFold2 for structure prediction beyond rigid globular proteins - Nature.com
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