Parkinson's disease: Disorder in the court - Nature.com

		BioNMR > NMR community > Online News
Parkinson's disease: Disorder in the court - Nature.com

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

02-08-2016, 02:17 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,732

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Parkinson's disease: Disorder in the court - Nature.com

Nature.com

Parkinson's disease: Disorder in the court
Nature.com
The native structure of the protein Î±-synuclein, which is implicated in Parkinson's disease, is controversial. In-cell nuclear magnetic resonance now shows that it remains disordered when loaded into living cells. See Article p.45 ...

Parkinson's disease: Disorder in the court - Nature.com
More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Parkinson's disease: Disorder in the court - Nature.com http://www.bionmr.com//t3.gstatic.com/images?q=tbn:ANd9GcTi-0IXId7SmGq23owc_1yYNHB6rH5ippkbzJJj6PmtjLZSZzrkKkZMxqgfeSI9TFget6P5glWb Nature.com <img alt="" height="1" width="1"> Parkinson's disease: Disorder in the court Nature.com The native structure of the protein Î±-synuclein, which is implicated in Parkinson's disease, is controversial. In-cell nuclear magnetic resonance now shows that it remains disordered when loaded into living cells. See Article p.45 ... Parkinson's disease: Disorder in the court - Nature.com	nmrlearner	Online News	0	02-05-2016 02:38 PM
Anti-malaria drugs could treat Parkinson's disease \| TODAYonline - TODAYonline http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcQPAcZ1zdhOvyDzvb1ZeHgphtdKS7UVWxHDrjU-HaTGUgcNGdB4jIX3uO9E9sYVckjWqEjKGqc TODAYonline <img alt="" height="1" width="1"> Anti-malaria drugs could treat Parkinson's disease \| TODAYonline TODAYonline Associate Professor at the Nanyang Technological University (NTU) School of Biological Sciences Yoon Ho Sup with a protein sample, which will then be inserted into a Nuclear Magnetic Resonance (NMR) spectroscopy machine to identify the compounds ... and more » Anti-malaria drugs could treat Parkinson's disease \| TODAYonline -...	nmrlearner	Online News	0	07-17-2015 02:13 AM
Plasma protein biomarkers of Alzheimer's disease endophenotypes in ... - Nature.com Plasma protein biomarkers of Alzheimer's disease endophenotypes in ... - Nature.com <img alt="" height="1" width="1"> Plasma protein biomarkers of Alzheimer's disease endophenotypes in ... Nature.com Volumes of the hippocampi and entorhinal cortices in the ANM cohort were obtained using FreeSurfer 5.1.0 (freely available from http://surfer.nmr.mgh.harvard.edu/) from 276 ANM subjects who had undergone structural MRI. These regions were selected as ... Read here	nmrlearner	Online News	0	06-17-2015 08:01 AM
Plasma protein biomarkers of Alzheimer's disease endophenotypes in ... - Nature.com Plasma protein biomarkers of Alzheimer's disease endophenotypes in ... - Nature.com <img alt="" height="1" width="1"> Plasma protein biomarkers of Alzheimer's disease endophenotypes in ... Nature.com Volumes of the hippocampi and entorhinal cortices in the ANM cohort were obtained using FreeSurfer 5.1.0 (freely available from http://surfer.nmr.mgh.harvard.edu/) from 276 ANM subjects who had undergone structural MRI. These regions were selected as ... Read here	nmrlearner	Online News	0	06-16-2015 07:24 PM
Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease - News-Medical.net Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease - News-Medical.net <img alt="" height="1" width="1" /> Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease News-Medical.net Kai Schlepckow and Harald Schwalbe at the Goethe University Frankfurt am Main have successfully used time-resolved NMR spectroscopic studies to follow what is happening to every individual amino acid as the prion protein molecules aggregateâ??an ... Read here	nmrlearner	Online News	0	08-16-2013 08:36 PM
Modulation of allostery by protein intrinsic disorder - Nature.com Modulation of allostery by protein intrinsic disorder - Nature.com <img alt="" height="1" width="1" /> Modulation of allostery by protein intrinsic disorder Nature.com Previous attempts at measuring dissociation constants (Kd) for E1A complexes with CBP by isothermal titration calorimetry (ITC) and nuclear magnetic resonance (NMR) failed because E1A is highly aggregation-prone. Even at concentrations as low as 10 Î¼M ... Read here	nmrlearner	Online News	0	06-19-2013 08:55 PM
Structure of key protein associated with Parkinson's disease determined - Science Codex <img alt="" height="1" width="1" /> Structure of key protein associated with Parkinson's disease determined Science Codex Pochapsky's lab was responsible for examining the protein using nuclear magnetic resonance, a sort of MRI for molecules, housed at the Landsman Research Facility. Alpha-synuclein is found in large quantities in the brain. ... and more » Structure of key protein associated with Parkinson's disease determined - Science Codex More...	nmrlearner	Online News	0	10-24-2011 11:06 PM
Structure of Parkinson's disease protein identified - Brandeis University http://nt3.ggpht.com/news/tbn/59yGiTFD_1OvxM/6.jpg Brandeis University <img alt="" height="1" width="1" /> Structure of Parkinson's disease protein identified Brandeis University Pochapsky's lab was responsible for examining the protein using nuclear magnetic resonance, a sort of MRI for molecules. Alpha-synuclein is found in large quantities in the brain. Its association with Parkinson's disease has stirred curiosity since it ... Structure of Parkinson's disease protein identified - Brandeis University	nmrlearner	Online News	0	10-21-2011 10:04 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off