[U. of Ottawa NMR Facility Blog] Comparison of Broadband Decoupling Schemes
Comparison of Broadband Decoupling Schemes
Many NMR measurements such as HSQC or HMQC rely on broadband X nucleus decoupling (X = 13C, 15N, 31P .... etc.).. Broadband decoupling schemes, using conventional rectangular pulses (e.g GARP) require fairly high power levels leading to undesired sample heating. They are also limited in their effective decoupling bandwidth. Adiabatic decoupling schemes use shaped adiabatic pulses and have become more and more common over the last couple of decades due, in large part, to the flexibility of modern NMR instruments to generate shaped pulses. ...
[NMR paper] NOAH: NMR Supersequences for Small Molecule Analysis and Structure Elucidation
NOAH: NMR Supersequences for Small Molecule Analysis and Structure Elucidation
Nested NMR experiments combining up to five conventional NMR pulse sequences into one supersequence are introduced. The core 2D NMR techniques routinely employed in small molecule NMR spectroscopy, such as HSQC, HMQC, HMBC, COSY, NOESY, TOCSY, and similar, can be recorded in a single measurement. In this way the data collection time may be dramatically reduced and sample throughput increased for basic NMR applications, such as structure elucidation and verification in synthetic, medicinal, and natural product...
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08-18-2017 04:59 PM
[NMR paper] NOAH - NMR Supersequences for Small Molecule Analysis and Structure Elucidation
NOAH - NMR Supersequences for Small Molecule Analysis and Structure Elucidation
Nested NMR experiments combining up to five conventional NMR pulse sequences into one supersequence are introduced. The core two-dimensional NMR techniques routinely employed in small molecule NMR, such as HSQC, HMQC, HMBC, COSY, NOESY, TOCSY and similar, can be recorded in a single measurement dramatically reducing the data collection time and increasing sample throughput for basic NMR applications to structure elucidation and verification in synthetic, medicinal and natural product chemistry.
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06-30-2017 06:14 PM
[NMR paper] A new broadband homonuclear mixing pulse for NMR with low applied power.
A new broadband homonuclear mixing pulse for NMR with low applied power.
A new broadband homonuclear mixing pulse for NMR with low applied power.
J Chem Phys. 2014 Jul 14;141(2):024201
Authors: Coote P, Leigh KE, Yu TY, Khaneja N, Wagner G, Arthanari H
Abstract
Broadband homonuclear mixing pulses with low radiofrequency power are essential for NMR spectroscopy of proteins and small molecules, especially for emerging applications in high field NMR. We have analytically designed a mixing pulse with high bandwidth-to-power ratio,...
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07-17-2014 12:17 PM
[NMR paper] Sequential protein NMR assignments in the liquid state via sequential data acquisition.
Sequential protein NMR assignments in the liquid state via sequential data acquisition.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Sequential protein NMR assignments in the liquid state via sequential data acquisition.
J Magn Reson. 2013 Dec 14;239C:23-28
Authors: Wiedemann C, Bellstedt P, Kirschstein A, Häfner S, Herbst C, Görlach M, Ramachandran R
Abstract
Two different NMR pulse schemes involving sequential (1)H data acquisition are...
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01-04-2014 01:39 AM
[NMR paper] Enhancing the resolution of multi-dimensional heteronuclear NMR spectra of intrinsically disordered proteins by homonuclear broadband decoupling.
Enhancing the resolution of multi-dimensional heteronuclear NMR spectra of intrinsically disordered proteins by homonuclear broadband decoupling.
Related Articles Enhancing the resolution of multi-dimensional heteronuclear NMR spectra of intrinsically disordered proteins by homonuclear broadband decoupling.
Chem Commun (Camb). 2013 Dec 23;
Authors: Helge Meyer N, Zangger K
Abstract
Limited spectral resolution in the proton dimension of NMR spectra is a severe problem in intrinsically disordered proteins. Here we show that homonuclear...
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12-25-2013 03:39 PM
[NMR paper] Sequential protein NMR assignments in the liquid state via sequential data acquisition
Sequential protein NMR assignments in the liquid state via sequential data acquisition
Publication date: Available online 14 December 2013
Source:Journal of Magnetic Resonance</br>
Author(s): Christoph Wiedemann , Peter Bellstedt , Anika Kirschstein , Sabine Häfner , Christian Herbst , Matthias Görlach , Ramadurai Ramachandran</br>
Two different NMR pulse schemes involving sequential 1H data acquisition are presented for achieving protein backbone sequential resonance assignments: (i) acquisition of 3D {HCCNH & HNCACONH} and (ii) collection of 3D {HNCOCANH &...
NMR supersequences with real-time homonuclear broadband decoupling: Sequential acquisition of protein and small ... - ScienceDirect
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