The neuronal S100B protein is a calcium-tuned suppressor of amyloid-? aggregation - Science Advances

		BioNMR > NMR community > Online News
The neuronal S100B protein is a calcium-tuned suppressor of amyloid-? aggregation - Science Advances

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

04-09-2019, 11:33 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,780

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

The neuronal S100B protein is a calcium-tuned suppressor of amyloid-? aggregation - Science Advances

The neuronal S100B protein is a calcium-tuned suppressor of amyloid-? aggregation - Science Advances

The neuronal S100B protein is a calcium-tuned suppressor of amyloid-? aggregation Science AdvancesAmyloid-? (A?) aggregation and neuroinflammation are consistent features in Alzheimer's disease (AD) and strong candidates for the initiation of ...

Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
The neuronal S100B protein is a calcium-tuned suppressor of amyloid-? aggregation - Science Advances The neuronal S100B protein is a calcium-tuned suppressor of amyloid-? aggregation - Science Advances The neuronal S100B protein is a calcium-tuned suppressor of amyloid-? aggregation Science AdvancesAmyloid-? (A?) aggregation and neuroinflammation are consistent features in Alzheimer's disease (AD) and strong candidates for the initiation of ... Read here	nmrlearner	Online News	0	01-07-2019 05:49 AM
The neuronal S100B protein is a calcium-tuned suppressor of amyloid-Î² aggregation - Science Advances The neuronal S100B protein is a calcium-tuned suppressor of amyloid-Î² aggregation - Science Advances <img alt="" height="1" width="1"> The neuronal S100B protein is a calcium-tuned suppressor of amyloid-Î² aggregation Science Advances We further speculated that the peak disappearances might also be caused either by the formation of a multimeric complex that is too large to be detected in the NMR experiments (although no precipitation was visible in the NMR titration experiments) or, ... Read here	nmrlearner	Online News	0	07-06-2018 09:40 AM
The neuronal S100B protein is a calcium-tuned suppressor of amyloid-Î² aggregation - Science Advances The neuronal S100B protein is a calcium-tuned suppressor of amyloid-Î² aggregation - Science Advances <img alt="" height="1" width="1"> The neuronal S100B protein is a calcium-tuned suppressor of amyloid-Î² aggregation Science Advances We further speculated that the peak disappearances might also be caused either by the formation of a multimeric complex that is too large to be detected in the NMR experiments (although no precipitation was visible in the NMR titration experiments) or, ... Read here	nmrlearner	Online News	0	07-06-2018 09:40 AM
Protein Science by DNA Sequencing: How Advances in Molecular Biology Are Accelerating Biochemistry Protein Science by DNA Sequencing: How Advances in Molecular Biology Are Accelerating Biochemistry http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.7b00886/20171020/images/medium/bi-2017-008868_0004.gif Biochemistry DOI: 10.1021/acs.biochem.7b00886 http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/bichaw/~4/vJJECwRnRgQ More...	nmrlearner	Journal club	0	10-24-2017 01:41 AM
[NMR paper] Distribution of amyloid-like and oligomeric species from protein aggregation kinetics Distribution of amyloid-like and oligomeric species from protein aggregation kinetics Amyloid fibrils and soluble oligomers are two types of protein aggregates associated with neurodegeneration. Classic therapeutic strategies try to prevent the nucleation and spread of amyloid fibrils, whilst diffusible oligomers have emerged as promising drug targets affecting downstream pathogenic processes. We developed a generic protein aggregation model and validate it against measured compositions of fibrillar and non-fibrillar assemblies of ataxin-3, a protein implicated in Machado-Joseph disease....	nmrlearner	Journal club	0	09-14-2017 11:59 AM
Deamidation Slows Curli Amyloid-Protein Aggregation Deamidation Slows Curli Amyloid-Protein Aggregation http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.7b00241/20170526/images/medium/bi-2017-00241u_0008.gif Biochemistry DOI: 10.1021/acs.biochem.7b00241 http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/bichaw/~4/kKsWxFjSPQ8 More...	nmrlearner	Journal club	0	05-27-2017 03:33 PM
Solid-State NMR and FTIR Study of a Neuronal Calcium Sensor (NCS) Protein, Recoverin Solid-State NMR and FTIR Study of a Neuronal Calcium Sensor (NCS) Protein, Recoverin Publication date: 28 January 2014 Source:Biophysical Journal, Volume 106, Issue 2, Supplement 1</br> Author(s): Kim Potvin-Fournier , Audrey Picard-Lafond , Melanie Schneider , Geneviève Valois-Paillard , Thierry Lefèvre , Philippe Calvez , Line Cantin , Christian Salesse , Michèle Auger</br> </br></br> </br></br> More...	nmrlearner	Journal club	0	01-29-2014 12:50 AM
[NMR paper] Backbone dynamics of the calcium-signaling protein apo-S100B as determined by 15N NMR Backbone dynamics of the calcium-signaling protein apo-S100B as determined by 15N NMR relaxation. Related Articles Backbone dynamics of the calcium-signaling protein apo-S100B as determined by 15N NMR relaxation. Biochemistry. 2001 Mar 27;40(12):3439-48 Authors: Inman KG, Baldisseri DM, Miller KE, Weber DJ Backbone dynamics of homodimeric apo-S100B were studied by (15)N nuclear magnetic resonance relaxation at 9.4 and 14.1 T. Longitudinal relaxation (T(1)), transverse relaxation (T(2)), and the (15)N- NOE were measured for 80 of 91 backbone...	nmrlearner	Journal club	0	11-19-2010 08:32 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off