Finishing the Jigsaw: Identifying How Drugs Interact with Molecules Could Lead to Better Treatments - Technology Networks
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Finishing the Jigsaw: Identifying How Drugs Interact with Molecules Could Lead to Better Treatments
Technology Networks
It adapts a technique known as ligand-based Nuclear Magnetic Resonance (NMR) spectroscopy to reveal which amino acids in the protein are involved in binding to the drug. They were able to do this by examining the drug and without having to label the ...
Finishing the Jigsaw:...
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NMR approaches in structure-based lead discovery: Recent developments and new frontiers for targeting multi-protein complexes
NMR approaches in structure-based lead discovery: Recent developments and new frontiers for targeting multi-protein complexes
Publication date: Available online 28 August 2014
Source:Progress in Biophysics and Molecular Biology</br>
Author(s): David M. Dias , Alessio Ciulli</br>
Nuclear magnetic resonance (NMR) spectroscopy is a pivotal method for structure-based and fragment-based lead discovery because it is one of the most robust techniques to provide information on protein structure, dynamics and interaction at an atomic level in solution. Nowadays, in most...
Mosquito Protein Discovery Could Lead to Treatments Against Life-Threatening Viruses - SciTechDaily
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