A modular approach to map out the conformational landscapes of unbound intrinsically disordered proteins | Proceedings of the National Academy of Sciences - pnas.org

		BioNMR > NMR community > Online News
A modular approach to map out the conformational landscapes of unbound intrinsically disordered proteins \| Proceedings of the National Academy of Sciences - pnas.org

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

06-04-2022, 09:42 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,778

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

A modular approach to map out the conformational landscapes of unbound intrinsically disordered proteins | Proceedings of the National Academy of Sciences - pnas.org

A modular approach to map out the conformational landscapes of unbound intrinsically disordered proteins | Proceedings of the National Academy of Sciences - pnas.org

A modular approach to map out the conformational landscapes of unbound intrinsically disordered proteins | Proceedings of the National Academy of Sciences pnas.org Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Accurate model of liquid–liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties \| Proceedings of the National Academy of Sciences - pnas.org Accurate model of liquid–liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties \| Proceedings of the National Academy of Sciences - pnas.org Accurate model of liquid–liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties \| Proceedings of the National Academy of Sciences pnas.org Read here	nmrlearner	Online News	0	06-03-2022 07:40 PM
Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins - pnas.org Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins - pnas.org Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins pnas.org Read here	nmrlearner	Online News	0	03-21-2022 04:01 AM
Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins - pnas.org Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins - pnas.org Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins pnas.org Read here	nmrlearner	Online News	0	01-10-2022 08:59 PM
Insights into heat shock protein machinery could point to interventions for neurodegenerative disease \| National Academy of Sciences - pnas.org Insights into heat shock protein machinery could point to interventions for neurodegenerative disease \| National Academy of Sciences - pnas.org Insights into heat shock protein machinery could point to interventions for neurodegenerative disease \| National Academy of Sciences pnas.org Read here	nmrlearner	Online News	0	07-03-2021 08:12 PM
Study reveals evolutionary origins of fold-switching protein \| National Academy of Sciences - pnas.org Study reveals evolutionary origins of fold-switching protein \| National Academy of Sciences - pnas.org Study reveals evolutionary origins of fold-switching protein \| National Academy of Sciences pnas.org Read here	nmrlearner	Online News	0	04-10-2021 03:40 AM
[NMR paper] NMR Spectroscopic Studies of the Conformational Ensembles of Intrinsically Disordered Proteins. NMR Spectroscopic Studies of the Conformational Ensembles of Intrinsically Disordered Proteins. Related Articles NMR Spectroscopic Studies of the Conformational Ensembles of Intrinsically Disordered Proteins. Adv Exp Med Biol. 2015;870:149-185 Authors: Kurzbach D, Kontaxis G, Coudevylle N, Konrat R Abstract Intrinsically disordered proteins (IDPs) are characterized by substantial conformational flexibility and thus not amenable to conventional structural biology techniques. Given their inherent structural flexibility NMR...	nmrlearner	Journal club	0	09-21-2015 03:01 PM
[NMR paper] An Approach to NMR Assignment of Intrinsically Disordered Proteins. An Approach to NMR Assignment of Intrinsically Disordered Proteins. An Approach to NMR Assignment of Intrinsically Disordered Proteins. Chemphyschem. 2015 Jan 30; Authors: Goradia N, Wiedemann C, Herbst C, Görlach M, Heinemann SH, Ohlenschläger O, Ramachandran R Abstract An efficient approach to NMR assignments in intrinsically disordered proteins is presented, making use of the good dispersion of cross peaks observed in - and -correlation spectra. The method involves the simultaneous collection of {3D (H)NCO(CAN)H and 3D...	nmrlearner	Journal club	0	02-03-2015 12:16 PM
[NMR paper] Exploring Free-Energy Landscapes of Intrinsically Disordered Proteins at Atomic Resolution Using NMR Spectroscopy. Exploring Free-Energy Landscapes of Intrinsically Disordered Proteins at Atomic Resolution Using NMR Spectroscopy. Exploring Free-Energy Landscapes of Intrinsically Disordered Proteins at Atomic Resolution Using NMR Spectroscopy. Chem Rev. 2014 Apr 11; Authors: Jensen MR, Zweckstetter M, Huang JR, Blackledge M PMID: 24725176	nmrlearner	Journal club	0	04-15-2014 10:38 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off