Streptonigrin Inhibits SENP1 and Reduces the ProteinLevel of Hypoxia-Inducible Factor 1? (HIF1?) in Cells
Streptonigrin Inhibits SENP1 and Reduces the ProteinLevel of Hypoxia-Inducible Factor 1? (HIF1?) in Cells
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.7b00947/20180301/images/medium/bi-2017-00947h_0006.gif
Biochemistry
DOI: 10.1021/acs.biochem.7b00947
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nmrlearner
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03-02-2018 03:20 PM
Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting
Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.7b00874/20171220/images/medium/bi-2017-00874m_0009.gif
Biochemistry
DOI: 10.1021/acs.biochem.7b00874
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nmrlearner
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12-20-2017 10:12 PM
Parkinson's disease: How toxic proteins damage healthy brain cells - Medical News Today
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Medical News Today
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Parkinson's disease: How toxic proteins damage healthy brain cells
Medical News Today
Scientists have gained insights into how toxic proteins disrupt healthy cell membranes in a process that leads to brain cell death in Parkinson's disease.
Researchers explore how toxic protein clusters linked to Parkinson's ...Brinkwire (press release)
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nmrlearner
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12-18-2017 11:19 PM
St. Jude analysis reveals how protein p53 triggers cancer cells to commit suicide - News-Medical.net
St. Jude analysis reveals how protein p53 triggers cancer cells to commit suicide - News-Medical.net
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St. Jude analysis reveals how protein p53 triggers cancer cells to commit suicide
News-Medical.net
In their studies, the researchers used a structural analysis technique called NMR spectroscopy to map the 3-D structure of p53 binding to BCL-xL. Their experiments also revealed in detail how one region of the p53 protein, called the DNA-binding domain ...
Detailed Studies Reveal how key Cancer-Fighting Protein is Held in CheckPR Web (press release)
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nmrlearner
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05-16-2014 07:46 AM
[NMR paper] High-Resolution Heteronuclear Multidimensional NMR of Proteins in Living Insect Cells Using a Baculovirus Protein Expression System.
High-Resolution Heteronuclear Multidimensional NMR of Proteins in Living Insect Cells Using a Baculovirus Protein Expression System.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-pubmed-acspubs.jpg Related Articles High-Resolution Heteronuclear Multidimensional NMR of Proteins in Living Insect Cells Using a Baculovirus Protein Expression System.
J Am Chem Soc. 2013 Jan 27;
Authors: Hamatsu J, O'Donovan D, Tanaka T, Shirai T, Hourai Y, Mikawa T, Ikeya T, Mishima M, Boucher W, Smith BO, Laue ED, Shirakawa M, Ito Y
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nmrlearner
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02-03-2013 10:19 AM
Mass Spec Dominating Protein Profiling - Genetic Engineering News
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Mass Spec Dominating Protein Profiling
Genetic Engineering News
â??In the field of proteomics today, the current methods of choice for molecular characterization are liquid chromatography combined with mass spectrometry, tandem mass spec, and nuclear magnetic resonance mass spectrometry,â?? said James Langridge, Ph.D., ...
Mass Spec Dominating Protein Profiling - Genetic Engineering News
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nmrlearner
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09-01-2011 07:23 PM
Suppression of phospholipid biosynthesis by cerulenin in the condensed Single-Protein-Production (cSPP) system
Suppression of phospholipid biosynthesis by cerulenin in the condensed Single-Protein-Production (cSPP) system
Abstract Using the single-protein-production (SPP) system, a protein of interest can be exclusively produced in high yield from its ACA-less gene in Escherichia coli expressing MazF, an ACA-specific mRNA interferase. It is thus feasible to study a membrane protein by solid-state NMR (SSNMR) directly in natural membrane fractions. In developing isotope-enrichment methods, we observed that 13C was also incorporated into phospholipids, generating spurious signals in SSNMR spectra....