Herpes hitches a ride on cellular protein LabnewsOnline
Using NMR, the team from the University of Manchester were able to produce images of a herpes protein interacting with a mouse cellular protein. ...
Herpes 3D: NMR reveals viral protein hijacking
Herpes 3D: NMR reveals viral protein hijacking
UK scientists have used NMR for the first time to develop a 3D picture of a herpes virus protein interacting with a key part of the human cellular machinery. The study improves our understanding of how the virus hijacks human cells and could eventually lead to new targets for drug therapy.
Source: Spectroscopynow.com
nmrlearner
General
0
01-15-2011 02:09 AM
Herpes 3D: NMR reveals viral protein hijacking - spectroscopyNOW.com
Herpes 3D: NMR reveals viral protein hijacking - spectroscopyNOW.com
<img alt="" height="1" width="1" />
Herpes 3D: NMR reveals viral protein hijacking
spectroscopyNOW.com
UK scientists have used solution-state NMR spectroscopy for the first time to develop a 3D picture of a herpes virus protein interacting with a key part of ...
Read here
nmrlearner
Online News
0
01-15-2011 02:09 AM
[NMR paper] Validation of the binding site structure of the cellular retinol-binding protein (CRB
Validation of the binding site structure of the cellular retinol-binding protein (CRBP) by ligand NMR chemical shift perturbations.
Related Articles Validation of the binding site structure of the cellular retinol-binding protein (CRBP) by ligand NMR chemical shift perturbations.
J Am Chem Soc. 2005 Apr 20;127(15):5310-1
Authors: Wang B, Merz KM
We have calculated proton chemical shift perturbations (CSPs) of retinol in the cellular retinol-binding protein (CRBP) through the use of a recently developed computational approach (Wang et al. J....
nmrlearner
Journal club
0
11-25-2010 08:21 PM
[NMR paper] NMR solution structure of type II human cellular retinoic acid binding protein: impli
NMR solution structure of type II human cellular retinoic acid binding protein: implications for ligand binding.
Related Articles NMR solution structure of type II human cellular retinoic acid binding protein: implications for ligand binding.
Biochemistry. 1998 Sep 15;37(37):12727-36
Authors: Wang L, Li Y, Abildgaard F, Markley JL, Yan H
The structure of human apo-cellular retinoic acid binding protein II (apo-CRABPII) in solution at pH 7.3 has been determined by NMR spectroscopy. The sequential assignments of the 1H, 13C, and 15N resonances...
nmrlearner
Journal club
0
11-17-2010 11:15 PM
Structure of key protein for cellular signal transduction elucidated - News-Medical.n
Structure of key protein for cellular signal transduction elucidated - News-Medical.net
<img alt="" height="1" width="1" />
Structure of key protein for cellular signal transduction elucidated
News-Medical.net
Using NMR spectroscopy, Professor Michael Sattler and his team elucidated the spatial structure of the Qua1 region of Sam68, which is responsible for the ...
and more »
Read here
nmrlearner
Online News
0
09-10-2010 12:58 PM
[NMR paper] NMR studies of fluororetinol analogs complexed to two homologous rat cellular retinol
NMR studies of fluororetinol analogs complexed to two homologous rat cellular retinol-binding proteins.
Related Articles NMR studies of fluororetinol analogs complexed to two homologous rat cellular retinol-binding proteins.
Biochim Biophys Acta. 1994 Sep 21;1208(1):136-44
Authors: Rong D, Lovey AJ, Rosenberger M, d'Avignon DA, Li E
Comparative 19F-NMR studies of fluororetinol analogs with rat cellular retinol binding protein II (CRBP II) and rat cellular retinol-binding protein (CRBP) were performed to probe differences in the binding...
nmrlearner
Journal club
0
08-22-2010 03:29 AM
[NMR paper] Inter-tryptophan distances in rat cellular retinol binding protein II by solid-state
Inter-tryptophan distances in rat cellular retinol binding protein II by solid-state NMR.
Related Articles Inter-tryptophan distances in rat cellular retinol binding protein II by solid-state NMR.
Biochemistry. 1993 May 4;32(17):4560-3
Authors: McDowell LM, Holl SM, Qian SJ, Li E, Schaefer J
Structural constraints for the tryptophans in rat cellular retinol binding protein II (CRBP II) have been obtained by rotational-echo double-resonance (REDOR) solid-state NMR. CRBP II was labeled with L-tryptophan and L-tryptophan. The 13C-19F dipolar...