[ASAP] Methyl-Based NMR Spectroscopy Methods for Uncovering Structural Dynamics in Large Proteins and Protein Complexes
Methyl-Based NMR Spectroscopy Methods for Uncovering Structural Dynamics in Large Proteins and Protein Complexes
https://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.8b00953/20181026/images/medium/bi-2018-00953s_0006.gif
Biochemistry
DOI: 10.1021/acs.biochem.8b00953
http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/bichaw/~4/VOv8DrY-3do
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nmrlearner
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11-25-2018 06:02 AM
[NMR paper] Uncovering the triggers for GPCR activation using solid-state NMR spectroscopy
Uncovering the triggers for GPCR activation using solid-state NMR spectroscopy
Publication date: April 2015
Source:Journal of Magnetic Resonance, Volume 253</br>
Author(s): Naoki Kimata , Philip J. Reeves , Steven O. Smith</br>
G protein-coupled receptors (GPCRs) span cell membranes with seven transmembrane helices and respond to a diverse array of extracellular signals. Crystal structures of GPCRs have provided key insights into the architecture of these receptors and the role of conserved residues. However, the question of how ligand binding induces the...
nmrlearner
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03-22-2015 06:36 PM
Watching A Helper Protein Do Its Job - The Biological SCENE
Watching A Helper Protein Do Its Job - The Biological SCENE
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Watching A Helper Protein Do Its Job
The Biological SCENE
â??This is an innovative approach that transcends the traditional techniques such as protein NMR and crystallography for detecting the highly mobile Ppant arm in action,â?? comments polyketide biosynthesis expert Shiou-Chuan (Sheryl) Tsai of the University ...
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nmrlearner
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08-22-2014 07:27 PM
Small molecule 'could treat paralysis by triggering nerve repair' - Medical News Today
http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcSc1ThQWactvqBySwVLfSER7i03wvjKS50O-SnIKWqb7dBmCSZjkecy4CIK8Yu0OCB6EeurVDw
Medical News Today
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Small molecule 'could treat paralysis by triggering nerve repair'
Medical News Today
Using nuclear magnetic resonance (NMR) technology, the team was able to closely analyze the configurations of the two p75 proteins. By introducing the p45 protein - which promotes nerve regeneration - they found it could break up the pairing of the p75 ...
Salk scientists uncover new clues to repairing an injured spinal...
nmrlearner
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08-06-2014 08:39 PM
Uncovering symmetry-breaking vector and reliability order for assigning secondary structures of proteins from atomic NMR chemical shifts in amino acids
Uncovering symmetry-breaking vector and reliability order for assigning secondary structures of proteins from atomic NMR chemical shifts in amino acids
Abstract Unravelling the complex correlation between chemical shifts of 13 C α, 13 C β, 13 C�, 1 H α, 15 N, 1 H N atoms in amino acids of proteins from NMR experiment and local structural environments of amino acids facilitates the assignment of secondary structures of proteins. This is an important impetus for both determining the three-dimensional structure and understanding the biological function of proteins. The previous...
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11-14-2011 08:45 AM
[KPWU blog] [PyMOL] Sidechain helper in the cartoon view
Sidechain helper in the cartoon view
Using cartoon view to present the protein secondary structures and tertiary structure is common and we also often see people present some sidechains of particular residues which may be important in some biological roles. In PyMOL, when sidechain atoms are presented in the “sticks mode” with the cartoon*scaffold, we always see the backbone atoms (e.g. http://stats.wordpress.com/b.gif?host=kpwu.wordpress.com&blog=76132&post=609&subd=kpwu&ref=&feed=1
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