Floppy but fast: Spaghetti-like proteins are surprisingly effective 'keys' - Phys.Org

		BioNMR > NMR community > Online News
Floppy but fast: Spaghetti-like proteins are surprisingly effective 'keys' - Phys.Org

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

10-09-2015, 04:49 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,733

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Floppy but fast: Spaghetti-like proteins are surprisingly effective 'keys' - Phys.Org

Floppy but fast: Spaghetti-like proteins are surprisingly effective 'keys' - Phys.Org

Phys.Org

Floppy but fast: Spaghetti-like proteins are surprisingly effective 'keys'
Phys.Org
The ultrafast and yet selective binding allows the receptor (gold) to rapidly travel through the pore filled with disordered proteins (blue) into the nucleus, while any unwanted molecules are kept outside. ... at the Institut de Biologie Structurale ...
European Molecular Biology LaboratoryEurekAlert (press release)

all 2 news articles »
Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
[NMR paper] Effective strategy to assign (1)H- (15)N heteronuclear correlation NMR signals from lysine side-chain NH3 (+) groups of proteins at low temperature. Effective strategy to assign (1)H- (15)N heteronuclear correlation NMR signals from lysine side-chain NH3 (+) groups of proteins at low temperature. Related Articles Effective strategy to assign (1)H- (15)N heteronuclear correlation NMR signals from lysine side-chain NH3 (+) groups of proteins at low temperature. J Biomol NMR. 2014 Aug 17; Authors: Esadze A, Zandarashvili L, Iwahara J Abstract Recent studies have shown that lysine side-chain NH3 (+) groups are excellent probes for NMR investigations of dynamics involving...	nmrlearner	Journal club	0	08-19-2014 11:21 AM
[NMR paper] Cost-effective method for the preparation of uniformly labeled myristoylated proteins for NMR measurements. Cost-effective method for the preparation of uniformly labeled myristoylated proteins for NMR measurements. Related Articles Cost-effective method for the preparation of uniformly labeled myristoylated proteins for NMR measurements. Protein Expr Purif. 2014 Mar 21; Authors: Kroupa T, Prchal J, Doležal M, Ruml T, Hrabal R Abstract Nuclear magnetic resonance (NMR) is a powerful technique for solving protein structures orstudying their interactions. However, it requires molecules labeled with NMR sensitive isotopes like carbon(13)C and...	nmrlearner	Journal club	0	03-26-2014 12:44 PM
Cost-effective method for the preparation of uniformly labeled myristoylated proteins for NMR measurements Cost-effective method for the preparation of uniformly labeled myristoylated proteins for NMR measurements Publication date: Available online 21 March 2014 Source:Protein Expression and Purification</br> Author(s): Tomáš Kroupa , Jan Prchal , Michal Doležal , Tomáš Ruml , Richard Hrabal</br> Nuclear magnetic resonance (NMR) is a powerful technique for solving protein structures orstudying their interactions. However, it requires molecules labeled with NMR sensitive isotopes like carbon13C and nitrogen15N. The recombinant expression of labeled proteins is simple...	nmrlearner	Journal club	0	03-22-2014 01:28 AM
A cost-effective look at proteins - with a little help from robotics - Cordis News http://www.bionmr.com//t3.gstatic.com/images?q=tbn:ANd9GcTypMhbcsoTBmkGzm1ZmzjTHj-b-AsNVL4y8L03Y0oBfj2cCZUDv2gZmGEzmim-0VUKjKStcwU Cordis News <img alt="" height="1" width="1" /> A cost-effective look at proteins - with a little help from robotics Cordis News Until now, a number of methods have been used to study static protein structures, including X-ray crystallography and nuclear magnetic resonance. However, these methods are of no use for proteins that are on the move; analytical methods, computer ... and more » A cost-effective look at proteins - with a little help from...	nmrlearner	Online News	0	09-14-2013 01:46 AM
Scientists find new source of versatility so 'floppy' proteins can get things done - EurekAlert (press release) Scientists find new source of versatility so 'floppy' proteins can get things done - EurekAlert (press release) <img alt="" height="1" width="1" /> Scientists find new source of versatility so 'floppy' proteins can get things done EurekAlert (press release) But IDPs don't connect willy-nilly with other proteins, and scientists have wondered how they regulate their diverse interactions. Wright's laboratory and others have been studying these interactions using a technique called nuclear magnetic resonance ... Read here	nmrlearner	Online News	0	06-21-2013 12:16 AM
ncIDP-assign: A SPARKY extension for the effective NMR assignment of intrinsically disordered proteins. ncIDP-assign: A SPARKY extension for the effective NMR assignment of intrinsically disordered proteins. ncIDP-assign: A SPARKY extension for the effective NMR assignment of intrinsically disordered proteins. Bioinformatics. 2011 Mar 3; Authors: Tamiola K, Mulder FA SUMMARY: We describe here the ncIDP-assign extension for the popular NMR assignment programme SPARKY, which aids in the sequence-specific resonance assignment of intrinsically disordered proteins (IDPs). The assignment plugin greatly facilitates the effective matching of a set of...	nmrlearner	Journal club	0	03-05-2011 01:02 PM
[NMR paper] Effective rotational correlation times of proteins from NMR relaxation interference. Effective rotational correlation times of proteins from NMR relaxation interference. Related Articles Effective rotational correlation times of proteins from NMR relaxation interference. J Magn Reson. 2006 Jan;178(1):72-6 Authors: Lee D, Hilty C, Wider G, Wüthrich K Knowledge of the effective rotational correlation times, tauc, for the modulation of anisotropic spin-spin interactions in macromolecules subject to Brownian motion in solution is of key interest for the practice of NMR spectroscopy in structural biology. The value of tauc enables...	nmrlearner	Journal club	0	12-01-2010 06:56 PM
[NMR paper] A simple and effective NMR cell for studies of encapsulated proteins dissolved in low A simple and effective NMR cell for studies of encapsulated proteins dissolved in low viscosity solvents. Related Articles A simple and effective NMR cell for studies of encapsulated proteins dissolved in low viscosity solvents. J Biomol NMR. 2002 Aug;23(4):311-6 Authors: Flynn PF, Milton MJ, Babu CR, Wand AJ Application of triple-resonance and isotope-edited-NOE methods to the study of increasingly larger macromolecules and their complexes remains a central goal of solution NMR spectroscopy. The slow reorientational motion of larger molecules...	nmrlearner	Journal club	0	11-24-2010 08:58 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off