More on Crystal Formation (This Time With Proteins) - Science Magazine (blog)
More on Crystal Formation (This Time With Proteins) - Science Magazine (blog)
<img alt="" height="1" width="1">
More on Crystal Formation (This Time With Proteins)
Science Magazine (blog)
I realize that I was just talking about crystal formation here the other day, but there's yet more news in the area, and it comes in the fiendishly difficult area of protein crystallography. All you have to do to appreciate the horrors of this field is ...
and more »
Read here
nmrlearner
Online News
0
04-13-2018 01:41 PM
A 3D time-shared NOESY experiment designed to provide optimal resolution for accurate assignment of NMR distance restraints in large proteins
A 3D time-shared NOESY experiment designed to provide optimal resolution for accurate assignment of NMR distance restraints in large proteins
Abstract
Structure determination of proteins by solution NMR has become an established method, but challenges increase steeply with the size of proteins. Notably, spectral crowding and signal overlap impair the analysis of cross-peaks in NOESY spectra that provide distance restraints for structural models. An optimal spectral resolution can alleviate overlap but requires prohibitively long experimental time...
nmrlearner
Journal club
0
11-11-2014 11:57 AM
[NMR paper] A 3D time-shared NOESY experiment designed to provide optimal resolution for accurate assignment of NMR distance restraints in large proteins.
A 3D time-shared NOESY experiment designed to provide optimal resolution for accurate assignment of NMR distance restraints in large proteins.
Related Articles A 3D time-shared NOESY experiment designed to provide optimal resolution for accurate assignment of NMR distance restraints in large proteins.
J Biomol NMR. 2014 Nov 9;
Authors: Mishra SH, Harden BJ, Frueh DP
Abstract
Structure determination of proteins by solution NMR has become an established method, but challenges increase steeply with the size of proteins. Notably,...
nmrlearner
Journal club
0
11-10-2014 10:59 PM
Speeding Up Drug Discovery with Rapid 3D Mapping of Proteins - Lab Manager Magazine
<img alt="" height="1" width="1" />
Speeding Up Drug Discovery with Rapid 3D Mapping of Proteins
Lab Manager Magazine
These amino acids gave off telltale structural clues when analyzed with nuclear magnetic resonance spectroscopy, a method for using the magnetic properties of atoms to determine a molecule's physical and chemical properties. "It was very difficult and ...
and more »
Speeding Up Drug Discovery with Rapid 3D Mapping of Proteins - Lab Manager Magazine
More...
nmrlearner
Online News
0
05-31-2012 03:59 AM
A New Tool to Reveal Structure of Proteins - Lab Manager Magazine
A New Tool to Reveal Structure of Proteins - Lab Manager Magazine
<img alt="" height="1" width="1" />
A New Tool to Reveal Structure of Proteins
Lab Manager Magazine
For roughly a decade, a technique called solid state nuclear magnetic resonance (NMR) spectroscopy has allowed researchers to detect the arrangements of atoms in proteins that defy study by traditional laboratory tools such as X-ray crystallography.
and more »
Read here
nmrlearner
Online News
0
03-20-2012 10:52 PM
[NMR paper] Dynamics of a de novo designed three-helix bundle protein studied by 15N, 13C, and 2H
Dynamics of a de novo designed three-helix bundle protein studied by 15N, 13C, and 2H NMR relaxation methods.
Related Articles Dynamics of a de novo designed three-helix bundle protein studied by 15N, 13C, and 2H NMR relaxation methods.
Biochemistry. 2001 Aug 14;40(32):9560-9
Authors: Walsh ST, Lee AL, DeGrado WF, Wand AJ
Understanding how the amino acid sequence of a polypeptide chain specifies a unique, functional three-dimensional structure remains an important goal, especially in the context of the emerging discipline of de novo protein...
For the First Time, DNA and Proteins Sensed by de Novo-Designed Nanopore - Lab Manager Magazine
Linear Mode
