[NMR paper] Membrane Protein Structures in Native Cellular Membranes Revealed by Solid-State NMR Spectroscopy
Membrane Protein Structures in Native Cellular Membranes Revealed by Solid-State NMR Spectroscopy
The structural characterization of membrane proteins within the cellular membrane environment is critical for understanding the molecular mechanism in their native functional context. However, conducting residue site-specific structural analysis of membrane proteins in native membranes by solid-state NMR faces challenges due to poor spectral sensitivity and serious interference from background protein signals. In this study, we present a new protocol that combines various strategies for...
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12-29-2023 03:15 PM
[NMR paper] Dynamics properties of membrane proteins in native cell membranes revealed by solid-state NMR spectroscopy
Dynamics properties of membrane proteins in native cell membranes revealed by solid-state NMR spectroscopy
Cell membranes provide an environment that is essential to the functions of membrane proteins. Cell membranes are mainly composed of proteins and highly diverse phospholipids. The influence of diverse lipid compositions of native cell membranes on the dynamics of the embedded membrane proteins has not been examined. Here we employ solid-state NMR to investigate the dynamics of E. coli Aquaporin Z (AqpZ) in its native inner cell membranes, and reveal the influence of diverse lipid...
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10-09-2021 06:32 PM
[ASAP] Gating Mechanism of Aquaporin Z in Synthetic Bilayers and Native Membranes Revealed by Solid-State NMR Spectroscopy
Gating Mechanism of Aquaporin Z in Synthetic Bilayers and Native Membranes Revealed by Solid-State NMR Spectroscopy
Yongxiang Zhao, Huayong Xie, Lili Wang, Yang Shen, Wei Chen, Benteng Song, Zhengfeng Zhang, Anmin Zheng, Qingsong Lin, Riqiang Fu, Jufang Wang, Jun Yang
https://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/jacs.8b03446/20180611/images/medium/ja-2018-03446h_0009.gif
Journal of the American Chemical Society
DOI: 10.1021/jacs.8b03446
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA...
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06-11-2018 07:38 PM
[NMR paper] Gating Mechanism of Aquaporin Z in Synthetic Bilayers and Native Membranes Revealed by Solid-state NMR Spectroscopy.
Gating Mechanism of Aquaporin Z in Synthetic Bilayers and Native Membranes Revealed by Solid-state NMR Spectroscopy.
Related Articles Gating Mechanism of Aquaporin Z in Synthetic Bilayers and Native Membranes Revealed by Solid-state NMR Spectroscopy.
J Am Chem Soc. 2018 May 25;:
Authors: Zhao Y, Xie H, Wang L, Shen Y, Chen W, Song B, Zhang Z, Zheng A, Lin Q, Fu R, Wang J, Yang J
Abstract
Aquaporin Z (AqpZ) is an integral membrane protein that facilitates transport of water across E. coli cells with a high rate. Previously, R189,...
Membrane proteins in their native habitat as seen by solid-state NMR spectroscopy
Membrane proteins in their native habitat as seen by solid-state NMR spectroscopy
Abstract
Membrane proteins play many critical roles in cells, mediating flow of material and information across cell membranes. They have evolved to perform these functions in the environment of a cell membrane, whose physicochemical properties are often different from those of common cell membrane mimetics used for structure determination. As a result, membrane proteins are difficult to study by traditional methods of structural biology, and they are significantly underrepresented in the protein structure...
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05-27-2015 10:39 AM
[NMR paper] Membrane proteins in their native habitat as seen by solid-state NMR spectroscopy.
Membrane proteins in their native habitat as seen by solid-state NMR spectroscopy.
Related Articles Membrane proteins in their native habitat as seen by solid-state NMR spectroscopy.
Protein Sci. 2015 May 13;
Authors: Brown LS, Ladizhansky V
Abstract
Membrane proteins play many critical roles in cells, mediating flow of material and information across cell membranes. They have evolved to perform these functions in the environment of a cell membrane, whose physicochemical properties are often different from those of common cell...
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05-15-2015 08:02 PM
Membrane proteins in their native habitat as seen by solid-state NMR spectroscopy
Membrane proteins in their native habitat as seen by solid-state NMR spectroscopy
Abstract
Membrane proteins play many critical roles in cells, mediating flow of material and information across cell membranes. They have evolved to perform these functions in the environment of a cell membrane, whose physicochemical properties are often different from those of common cell membrane mimetics used for structure determination. As a result, membrane proteins are difficult to study by traditional methods of structural biology, and they are significantly underrepresented in the protein...
Dynamics properties of membrane proteins in native cell membranes revealed by solid-state NMR spectroscopy - sciencedirect.com
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