Drug target for Ebola-like viruses identified - Economic Times

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Drug target for Ebola-like viruses identified - Economic Times

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Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

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TALOS

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Flexibility from chemical shifts:

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Methyl S2

B-factor

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Chemical shifts prediction:

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Shiftx2

Sparta+

Camshift

CH3shift- Methyl

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ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

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05-11-2015, 09:06 PM

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Drug target for Ebola-like viruses identified - Economic Times

Drug target for Ebola-like viruses identified
Economic Times
Researchers used Nuclear Magnetic Resonance (NMR) spectroscopy studies to investigate the structural properties of an important viral protein required for virulence of the Rift Valley fever virus, a virus that causes infections in both humans and ...

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Drug target for Ebola-like viruses identified - Economic Times
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