[NMR paper] Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase
Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase
The role of biomolecular condensates in regulating biological function and the importance of dynamic interactions involving intrinsically disordered protein regions (IDRs) in their assembly are increasingly appreciated. While computational and theoretical approaches have provided significant insights into IDR phase behavior, establishing the critical interactions that govern condensation with atomic resolution through experiment is more difficult, given the lack of applicability of standard...
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06-02-2021 05:10 PM
Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase [Biophysics and Computational Biology]
Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase
Tae Hun Kim, Brandon J. Payliss, Michael L. Nosella, Ian T. W. Lee, Yuki Toyama, Julie D. Forman-Kay, Lewis E. Kay...
Date: 2021-06-01
The role of biomolecular condensates in regulating biological function and the importance of dynamic interactions involving intrinsically disordered protein regions (IDRs) in their assembly are increasingly appreciated. While computational and theoretical approaches have provided significant insights into IDR phase behavior, establishing the critical...
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06-01-2021 11:42 PM
Direct Observation of the Ion-Pair Dynamics at a Protein–DNAInterface by NMR Spectroscopy
Direct Observation of the Ion-Pair Dynamics at a Protein–DNAInterface by NMR Spectroscopy
Kurtis M. Anderson, Alexandre Esadze, Mariappan Manoharan, Rafael Bru?schweiler, David G. Gorenstein and Junji Iwahara
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja312314b/aop/images/medium/ja-2012-12314b_0006.gif
Journal of the American Chemical Society
DOI: 10.1021/ja312314b
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/jacsat/~4/DG3FmZefxcE
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02-27-2013 06:45 AM
[NMR paper] Direct observation of the ion-pair dynamics at a protein-DNA interface by NMR spectroscopy.
Direct observation of the ion-pair dynamics at a protein-DNA interface by NMR spectroscopy.
Related Articles Direct observation of the ion-pair dynamics at a protein-DNA interface by NMR spectroscopy.
J Am Chem Soc. 2013 Feb 14;
Authors: Anderson KM, Esadze A, Manoharan M, Bruschweiler R, Gorenstein DG, Iwahara J
Abstract
Ion pairing is one of the most fundamental chemical interactions and is essential for molecular recognition by biological macromolecules. From an experimental standpoint, very little is known to date about ion-pair...
Direct observation of structure and dynamics during phase separation of an elastomeric protein - pnas.org
Linear Mode
