Detailed Studies Reveal how key Cancer-Fighting Protein is Held in Check - Broadway World

		BioNMR > NMR community > Online News
Detailed Studies Reveal how key Cancer-Fighting Protein is Held in Check - Broadway World

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

05-26-2014, 09:25 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,778

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Detailed Studies Reveal how key Cancer-Fighting Protein is Held in Check - Broadway World

Detailed Studies Reveal how key Cancer-Fighting Protein is Held in Check - Broadway World

Detailed Studies Reveal how key Cancer-Fighting Protein is Held in Check
Broadway World
In their studies, the researchers used a structural analysis technique called NMR spectroscopy to map the 3-D structure of p53 binding to BCL-xL. Their experiments also revealed in detail how one region of the p53 protein, called the DNA-binding domain ...

and more »
Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Detailed Studies Reveal How Key Cancer-Fighting Protein Is Held in Check - Newswise (press release) Detailed Studies Reveal How Key Cancer-Fighting Protein Is Held in Check - Newswise (press release) <img alt="" height="1" width="1" /> Detailed Studies Reveal How Key Cancer-Fighting Protein Is Held in Check Newswise (press release) ... Studies Reveal How Key Cancer-Fighting Protein Is Held in Check. St. Jude Children's Research Hospital analysis reveals how the protein p53, which triggers cancer cells to commit suicide, attaches to its regulatory molecule; findings could lead to ... Read here	nmrlearner	Online News	0	05-22-2014 01:48 AM
Detailed studies reveal how key cancer-fighting protein is held in check - HealthCanal.com Detailed studies reveal how key cancer-fighting protein is held in check - HealthCanal.com <img alt="" height="1" width="1" /> Detailed studies reveal how key cancer-fighting protein is held in check HealthCanal.com In their studies, the researchers used a structural analysis technique called NMR spectroscopy to map the 3-D structure of p53 binding to BCL-xL. Their experiments also revealed in detail how one region of the p53 protein, called the DNA-binding domain ... and more » Read here	nmrlearner	Online News	0	05-17-2014 01:15 PM
Detailed Studies Reveal how key Cancer-Fighting Protein is Held in Check - Virtual-Strategy Magazine (press release) Detailed Studies Reveal how key Cancer-Fighting Protein is Held in Check - Virtual-Strategy Magazine (press release) <img alt="" height="1" width="1" /> Detailed Studies Reveal how key Cancer-Fighting Protein is Held in Check Virtual-Strategy Magazine (press release) St. Jude Children's Research Hospital analysis reveals how the protein p53, which triggers cancer cells to commit suicide, attaches to its regulatory molecule; findings could lead to drugs to unleash p53 to battle a range of cancers. Memphis, Tenn ... and more » Read here	nmrlearner	Online News	0	05-15-2014 07:23 PM
Free-electron lasers reveal detailed architecture of proteins - R & D Magazine Free-electron lasers reveal detailed architecture of proteins - R & D Magazine http://www.bionmr.com//nt1.ggpht.com/news/tbn/1ed-82XzQnyMGM/6.jpg R & D Magazine <img alt="" height="1" width="1" /> Free-electron lasers reveal detailed architecture of proteins R & D Magazine An international team of researchers has recently analyzed protein crystals using ... of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. and more »	nmrlearner	Online News	0	06-13-2012 11:34 AM
[NMR tweet] @scifri Check this out, MRI with no magnets using SQUID! #Star Trek hand held body scanners closer than we think. http://bit.ly/kNOG89 @scifri Check this out, MRI with no magnets using SQUID! #Star Trek hand held body scanners closer than we think. http://bit.ly/kNOG89 Published by Leighton_Smith (Leighton Smith) on 2011-05-20T17:13:04Z Source: Twitter	nmrlearner	Twitter NMR	0	05-20-2011 06:02 PM
[NMR paper] NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyas NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system. Related Articles NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system. Biochemistry. 2004 Jul 6;43(26):8322-32 Authors: Di Lello P, Benison GC, Valafar H, Pitts KE, Summers AO, Legault P, Omichinski JG Mercury resistant bacteria have developed a system of two enzymes (MerA and MerB), which allows them to efficiently...	nmrlearner	Journal club	0	11-24-2010 09:51 PM
[NMR paper] TROSY-NMR studies of the 91kDa TRAP protein reveal allosteric control of a gene regul TROSY-NMR studies of the 91kDa TRAP protein reveal allosteric control of a gene regulatory protein by ligand-altered flexibility. Related Articles TROSY-NMR studies of the 91kDa TRAP protein reveal allosteric control of a gene regulatory protein by ligand-altered flexibility. J Mol Biol. 2002 Oct 25;323(3):463-73 Authors: McElroy C, Manfredo A, Wendt A, Gollnick P, Foster M The tryptophan biosynthesis genes of several Bacilli are controlled through terminator/anti-terminator transcriptional attenuation. This process is regulated by...	nmrlearner	Journal club	0	11-24-2010 08:58 PM
Studies probe key flu protein - Chemistry World Studies probe key flu protein - Chemistry World http://nt2.ggpht.com/news/tbn/pqKKK9V276IW3M/6.jpg Chemistry World <img alt="" height="1" width="1" /> Studies probe key flu protein Chemistry World Both studies, published back-to-back in Science, use solid-state nuclear magnetic resonance to probe the fine structure of the M2 channel protein and ...	nmrlearner	Online News	0	10-21-2010 07:11 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off