UMass Amherst Biochemists Simulate a Protein-Folding Chaperone's Functional Dance - UMass News and Media Relations
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UMass News and Media Relations
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UMass Amherst Biochemists Simulate a Protein-Folding Chaperone's Functional Dance
UMass News and Media Relations
Gierasch says Wenli Meng, a master of nuclear magnetic resonance (NMR) techniques, obtained NMR data that validated the simulations. The linker is just 12 amino acids long, and Meng was able to directly extract linker information from among 636 amino ...
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08-29-2017 05:35 PM
Biochemists simulate a protein-folding chaperone's functional dance - Phys.Org
Biochemists simulate a protein-folding chaperone's functional dance - Phys.Org
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Phys.Org
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Biochemists simulate a protein-folding chaperone's functional dance
Phys.Org
A recent advance in understanding of the role of an interdomain linker in Hsp70 chaperones by Gierasch's group at UMass Amherst required clever computational techniques, massive computing power and masterful use of NMR, she says. Credit: UMass ...
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08-29-2017 05:35 PM
Protein dance on nanoparticle surface revealed - The Biological SCENE
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Protein dance on nanoparticle surface revealed
The Biological SCENE
The growing use of nanomaterials in biomedical applications makes understanding nanoparticle-protein interactions an important goal. Nuclear magnetic resonance spectroscopy is a promising way to probe such interactions. But because of the huge size ...
Protein dance on nanoparticle surface revealed - The Biological SCENE
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05-16-2016 05:53 PM
Researchers uncover how small heat shock protein interacts with other proteins - News-Medical.net
Researchers uncover how small heat shock protein interacts with other proteins - News-Medical.net
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Researchers uncover how small heat shock protein interacts with other proteins
News-Medical.net
... in uncovering precisely this mechanism. Using a refined procedure of solid-state nuclear magnetic resonance spectroscopy (solid-state NMR), they managed, for the first time ever, to identify the sites in the alpha-B-crystallin that attach to the ...
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10-16-2015 12:49 AM
Scientists Paint New Picture of Dance Between Protein and Binding Partners - Science Daily (press release)
Scientists Paint New Picture of Dance Between Protein and Binding Partners - Science Daily (press release)
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Scientists Paint New Picture of Dance Between Protein and Binding Partners
Science Daily (press release)
The new study -- which used a number of complementary technologies including NMR spectroscopy and hydrogen/deuterium exchange (HDX) coupled to mass spectrometery, combined with previous x-ray crystallography analyses -- provides detailed insights into ...
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01-23-2012 03:12 AM
Scripps Research scientists paint new picture of dance between protein and ... - Science Codex
Scripps Research scientists paint new picture of dance between protein and ... - Science Codex
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Science Codex
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Scripps Research scientists paint new picture of dance between protein and ...
Science Codex
The new studyâ??which used a number of complementary technologies including NMR spectroscopy and hydrogen/deuterium exchange (HDX) coupled to mass spectrometery, combined with previous x-ray crystallography analysesâ??provides detailed insights into the ...
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01-11-2012 04:03 AM
[NMR paper] Calbindin D28K interacts with Ran-binding protein M: identification of interacting do
Calbindin D28K interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy.
Related Articles Calbindin D28K interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy.
Biochem Biophys Res Commun. 2003 Apr 18;303(4):1186-92
Authors: Lutz W, Frank EM, Craig TA, Thompson R, Venters RA, Kojetin D, Cavanagh J, Kumar R
Calbindin D(28K) is an EF-hand containing protein that plays a vital role in neurological function. We now show that calcium-loaded calbindin D(28K) interacts...