[NMR paper] Short two-armed lanthanide-binding tags for paramagnetic NMR spectroscopy based on chiral 1,4,7,10-tetrakis(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane scaffolds.
Short two-armed lanthanide-binding tags for paramagnetic NMR spectroscopy based on chiral 1,4,7,10-tetrakis(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane scaffolds.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.rsc.org-images-entities-char_z_RSClogo.gif Short two-armed lanthanide-binding tags for paramagnetic NMR spectroscopy based on chiral 1,4,7,10-tetrakis(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane scaffolds.
Chem Commun (Camb). 2017 Nov 22;:
Authors: Lee MD, Dennis ML, Graham B, Swarbrick JD
...
nmrlearner
Journal club
0
11-24-2017 04:57 AM
[NMR paper] Structure-based design of scaffolds targeting PDE10A by INPHARMA-NMR.
Structure-based design of scaffolds targeting PDE10A by INPHARMA-NMR.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-pubmed-acspubs.jpg Related Articles Structure-based design of scaffolds targeting PDE10A by INPHARMA-NMR.
J Chem Inf Model. 2017 May 31;:
Authors: Codutti L, Grimaldi M, Carlomagno T
Abstract
Phosphodiesterases (PDE) hydrolyze both cyclic AMP and GMP (cAMP/cGMP) and are responsible for the regulation of their levels in a multitude of cellular functions. PDE10A is...
nmrlearner
Journal club
0
06-02-2017 08:33 PM
De novo protein structure determination from near-atomic-resolution cryo-EM maps - Nature.com
De novo protein structure determination from near-atomic-resolution cryo-EM maps - Nature.com
<img alt="" height="1" width="1">
De novo protein structure determination from near-atomic-resolution cryo-EM maps
Nature.com
Despite these developments, little progress has been made in de novo model building into near-atomic-resolution cryo-EM density maps. Structural interpretation of cryo-EM maps typically starts with fitting an atomic X-ray or NMR structure into the map5.
Read here
nmrlearner
Online News
0
02-24-2015 02:48 PM
[NMR paper] Optimization of the methods for small peptide solution structure determination by NMR spectroscopy
From Mendeley Biomolecular NMR group:
Optimization of the methods for small peptide solution structure determination by NMR spectroscopy
Mol Biol (Mosk) (2010). Volume: 44, Issue: 6. Pages: 1075-1085. A N Istrate, A B Mantsyzov, S A Kozin, V I Pol'shakov et al.
NMR spectroscopy was recognized as a method of protein structure determination in solution. However, determination of the conformation of small peptides, which undergo fast molecular motions, remains a challenge. This is mainly caused by impossibility to collect required quantity of the distance and dihedral angle restraints...
nmrlearner
Journal club
0
11-15-2012 06:46 PM
[NMR paper] Optimization of the methods for small peptide solution structure determination by NMR spectroscopy
From Mendeley Biomolecular NMR group:
Optimization of the methods for small peptide solution structure determination by NMR spectroscopy
Mol Biol (Mosk) (2010). Volume: 44, Issue: 6. Pages: 1075-1085. A N Istrate, A B Mantsyzov, S A Kozin, V I Pol'shakov et al.
NMR spectroscopy was recognized as a method of protein structure determination in solution. However, determination of the conformation of small peptides, which undergo fast molecular motions, remains a challenge. This is mainly caused by impossibility to collect required quantity of the distance and dihedral angle restraints...
Cryo-EM structure determination of small proteins by nanobody-binding scaffolds (Legobodies) - pnas.org
Linear Mode
