Crowd-sourced computer network delves into protein structure, seeks new disease therapies - Phys.Org

		BioNMR > NMR community > Online News
Crowd-sourced computer network delves into protein structure, seeks new disease therapies - Phys.Org

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

05-09-2019, 11:40 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,734

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Crowd-sourced computer network delves into protein structure, seeks new disease therapies - Phys.Org

Crowd-sourced computer network delves into protein structure, seeks new disease therapies - Phys.Org

Crowd-sourced computer network delves into protein structure, seeks new disease therapies Phys.OrgWhen Greg Bowman presents a slideshow about the proteins he studies, their 3-D shapes and folding patterns play out as animations on a big screen.

Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
A Lipid-binding Protein is a Target for New Cancer Therapies - R & D Magazine A Lipid-binding Protein is a Target for New Cancer Therapies - R & D Magazine A Lipid-binding Protein is a Target for New Cancer Therapies R & D MagazineThe results identified a specific nook in the SET protein's shape that provides a snug fit for ceramide. Read here	nmrlearner	Online News	0	05-02-2019 06:55 PM
Computer model may help scientists split up, reassemble proteins on command - Phys.org Computer model may help scientists split up, reassemble proteins on command - Phys.org Computer model may help scientists split up, reassemble proteins on command Phys.orgSplitting up and getting back together is always hard to do, but for proteins, it's almost impossible. Read here	nmrlearner	Online News	0	01-07-2019 05:49 AM
Computer model for designing protein sequences optimized to bind to drug targets - Phys.org Computer model for designing protein sequences optimized to bind to drug targets - Phys.org Computer model for designing protein sequences optimized to bind to drug targets Phys.orgDesigning synthetic proteins that can act as drugs for cancer or other diseases can be a tedious process: It generally involves creating a library of millions of ... Read here	nmrlearner	Online News	0	01-07-2019 05:49 AM
Light microscopy provides a deep look into protein structure - Phys.org - Phys.Org Light microscopy provides a deep look into protein structure - Phys.org - Phys.Org http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcQG69FMdjaOzVdvO8fNDx9c1t6uv0SeGKAywKjRdVRRma0SZH4sGlq9-_q3JW8xkTHitn6biYqD Phys.Org <img alt="" height="1" width="1"> Light microscopy provides a deep look into protein structure - Phys.org Phys.Org Light microscopy continues to reveal the microscopic world at an ever increasing resolution. Using a new method coined COLD, scientists at the Max Planck ... and more »	nmrlearner	Online News	0	01-25-2017 11:13 PM
Discovery of molecular protection linked to a degenerative neuromuscular disease - Phys.Org http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcRAnr-pPxtTafemGBGJsWWWp_qUDzbH9ZYUIMB-iOoozI3jwJv0Y9T0O7WmI-r4WFwLNuw7oTk Phys.Org <img alt="" height="1" width="1"> Discovery of molecular protection linked to a degenerative neuromuscular disease Phys.Org Thanks to access to one of the main Nuclear Magnetic Resonance facilities in Europe, located at the University of Florence, for the first time the scientists have studied the protein in a test tube. They have observed that right next to the glutamine ... and more » Discovery of molecular protection linked to a...	nmrlearner	Online News	0	06-10-2016 10:49 PM
Study reveals insights into protein linked to cancer and Alzheimer's disease - Phys.Org http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcSWI4MEyAKap5sPkmjZDVOz54ftSxtRd9JGH5zRAazKibUp4bqE85WneiO-T0Zw4Yodm98XzkWk Phys.Org <img alt="" height="1" width="1"> Study reveals insights into protein linked to cancer and Alzheimer's disease Phys.Org Using high-field nuclear magnetic resonance (NMR) spectroscopy, Peng and his group propose answers to both questions. He explained with a metaphor. "When Pin 1 is by itself, its two domains, call them 'A' and 'B,' have greater physical contact," he said. and more » Study reveals insights into protein linked to cancer...	nmrlearner	Online News	0	06-07-2016 12:27 AM
Scientists Observe Structure of Protein That Plays Major Role in Huntington's Disease, Opening Door to Finding Cause ... - Huntington's Disease News Scientists Observe Structure of Protein That Plays Major Role in Huntington's Disease, Opening Door to Finding Cause ... - Huntington's Disease News http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcTwPt0kkc7URsZZYlq-KqB_9CkWqZ-RqmOnDrrW5h7hGiXSmY3KB8xsPpoKBTVsqkUarvvUCVGj Huntington's Disease News <img alt="" height="1" width="1"> Scientists Observe Structure of Protein That Plays Major Role in Huntington's Disease, Opening Door to Finding Cause ... Huntington's Disease News Leibniz-Institut fÃ¼r Molekulare Pharmakologie (FMP) researchers used a combination of nuclear magnetic...	nmrlearner	Online News	0	02-10-2016 09:28 PM
[NMR paper] Diazole-based powdered cocrystal featuring a helical hydrogen-bonded network: Structure determination from PXRD, solid-state NMR and computer modeling. Diazole-based powdered cocrystal featuring a helical hydrogen-bonded network: Structure determination from PXRD, solid-state NMR and computer modeling. Related Articles Diazole-based powdered cocrystal featuring a helical hydrogen-bonded network: Structure determination from PXRD, solid-state NMR and computer modeling. Solid State Nucl Magn Reson. 2014 Dec 30; Authors: Sardo M, Santos SM, Babaryk AA, López C, Alkorta I, Elguero J, Claramunt RM, Mafra L Abstract We present the structure of a new equimolar 1:1 cocrystal formed by...	nmrlearner	Journal club	0	01-22-2015 01:20 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off