This Is The Closest Look We've Ever Had at The Proteins Linked to Alzheimer's Disease ScienceAlert
Extra readings from solid-state nuclear magnetic resonance (NMR) spectroscopy and X-ray diffraction experiments helped to validate the data and the atomic structure, producing a computer rendering that's the most accurate we've ever seen, down to a ...
Discovery of molecular protection linked to a degenerative neuromuscular disease - Science Daily
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Science Daily
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Discovery of molecular protection linked to a degenerative neuromuscular disease
Science Daily
Thanks to access to one of the main Nuclear Magnetic Resonance facilities in Europe, located at the University of Florence, for the first time the scientists have studied the protein in a test tube. They have observed that right next to the glutamine ...
Discovery of molecular protection linked to a...
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06-12-2016 02:35 AM
Discovery of molecular protection linked to a degenerative neuromuscular disease - Phys.Org
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Phys.Org
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Discovery of molecular protection linked to a degenerative neuromuscular disease
Phys.Org
Thanks to access to one of the main Nuclear Magnetic Resonance facilities in Europe, located at the University of Florence, for the first time the scientists have studied the protein in a test tube. They have observed that right next to the glutamine ...
and more »
Discovery of molecular protection linked to a...
nmrlearner
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06-10-2016 10:49 PM
Study reveals insights into protein linked to cancer and Alzheimer's disease - Phys.Org
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Phys.Org
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Study reveals insights into protein linked to cancer and Alzheimer's disease
Phys.Org
Using high-field nuclear magnetic resonance (NMR) spectroscopy, Peng and his group propose answers to both questions. He explained with a metaphor. "When Pin 1 is by itself, its two domains, call them 'A' and 'B,' have greater physical contact," he said.
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Study reveals insights into protein linked to cancer...
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06-07-2016 12:27 AM
Study reveals insights into protein linked to cancer, Alzheimer's disease - Science Daily
Study reveals insights into protein linked to cancer, Alzheimer's disease - Science Daily
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Study reveals insights into protein linked to cancer, Alzheimer's disease
Science Daily
NMR-based model for Pin1 (â??Aâ?? and â??Bâ?? globular domains), and its interaction with its â??disorderedâ?? protein targets pertinent to cancer and Alzheimer's disease (green). The Pin1 â??Aâ?? and â??Bâ?? domains specialize in peptidyl-prolyl isomerase activity and ...
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nmrlearner
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06-05-2016 02:18 AM
Study reveals insights into protein linked to cancer and Alzheimer's disease - ND Newswire
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ND Newswire
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Study reveals insights into protein linked to cancer and Alzheimer's disease
ND Newswire
Using high-field nuclear magnetic resonance (NMR) spectroscopy, Peng and his group propose answers to both questions. He explained with a metaphor. â??When Pin 1 is by itself, its two domains, call them 'A' and 'B,' have greater physical contact,â?? he said.
and more »
Study reveals insights into protein linked to...
nmrlearner
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06-03-2016 04:52 PM
Study Reveals Insights Into Protein Linked to Cancer and Alzheimer's Disease - Newswise (press release)
Study Reveals Insights Into Protein Linked to Cancer and Alzheimer's Disease - Newswise (press release)
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Study Reveals Insights Into Protein Linked to Cancer and Alzheimer's Disease
Newswise (press release)
Yet they are increasingly recognized as functional units, figuring prominently in cancer-related proteins. So a second question has been, how does Pin1 interact with those disordered sites? Using high-field nuclear magnetic resonance (NMR) spectroscopy ...
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nmrlearner
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06-03-2016 04:52 PM
Alzheimer's disease: NMR pinpoints genetic clue
Alzheimer's disease: NMR pinpoints genetic clue
http://www.spectroscopynow.com/common/images/thumbnails/1438cadfde3.jpgResearchers have turned to solution NMR spectroscopy to help them characterise the structure and dynamics of the transmembrane portion of the protein amyloid precursor protein, APP, of which there are two genetic variants linked to familial, or hereditary Alzheimer's disease.
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01-15-2014 05:05 AM
Alzheimer's analysed: New clues in brain disease
Alzheimer's analysed: New clues in brain disease
http://www.spectroscopynow.com/common/images/thumbnails/13af4d7f690.jpgRecent studies have added weight to the idea that amyloid-beta is a causative agent in Alzheimer's disease rather than the plaques formed from these chunks of misfolded peptide that deposit in the diseased brain. Now, European researchers have used REAPDOR solid-state NMR spectroscopy to analyse the hydrogen bonds in the tiny fibrils of amyloid-beta peptide, offering another perspective on this neurodegenerative disorder.
Source: Spectroscopynow.com