Can Depression, Obesity, and Pain Be Fought By Blocking One Protein? - Anti Aging News

		BioNMR > NMR community > Online News
Can Depression, Obesity, and Pain Be Fought By Blocking One Protein? - Anti Aging News

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

04-03-2019, 01:27 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,777

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Can Depression, Obesity, and Pain Be Fought By Blocking One Protein? - Anti Aging News

Can Depression, Obesity, and Pain Be Fought By Blocking One Protein? Anti Aging NewsNew research claims to have found a drug that may be able to tackle depression, obesity, and chronic pain which are three of the most pressing health concerns; ...

Can Depression, Obesity, and Pain Be Fought By Blocking One Protein? - Anti Aging News
More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Can blocking a single protein tackle depression, obesity, and pain? - Medical News Today Can blocking a single protein tackle depression, obesity, and pain? Medical News TodayDepression, obesity, and chronic pain are some of the most pressing global health concerns. New research may have found a drug that could one day tackle all ... Can blocking a single protein tackle depression, obesity, and pain? - Medical News Today More...	nmrlearner	Online News	0	04-02-2019 02:58 PM
Depression, obesity, chronic pain could be treated by targeting the same key protein - Science Daily Depression, obesity, chronic pain could be treated by targeting the same key protein Science DailyMajor depression, obesity and chronic pain are all linked to the effects of one protein, called FKBP51. Researchers have now developed a highly selective ... Depression, obesity, chronic pain could be treated by targeting the same key protein - Science Daily More...	nmrlearner	Online News	0	04-02-2019 01:35 AM
Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs - News-Medical.net http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcR8JLyCl_TBn74dosW54RiWq5k6RI16xRp7_Wl1EZxjE6GeQlHlSBgXMZWOd0Zi-Qp8mh6JAYmY News-Medical.net <img alt="" height="1" width="1"> Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs News-Medical.net To watch a kinase called mitogen-activated protein kinase (MAPK) p38 in action, the researchers used nuclear magnetic resonance (NMR) spectroscopy. All necessary molecules had to bind to p38 for the enzyme to become active. Only then could the ... Interfering with enzyme's movement may be new...	nmrlearner	Online News	0	05-16-2018 03:42 PM
Pain on the brain: NMR tracks analgesics Pain on the brain: NMR tracks analgesics http://www.spectroscopynow.com/common/images/thumbnails/153cce93d02.jpgNuclear magnetic resonance spectroscopy (NMR) can be used to measure brain metabolites following administration of painkillers and so provide a useful way to evaluate objectively the analgesic effect as well as to study the mode of action of old and new types of painkiller. Read the rest at Spectroscopynow.com	nmrlearner	General	0	04-01-2016 09:13 AM
A Novel Inhibitor of the Obesity-Related Protein FTO A Novel Inhibitor of the Obesity-Related Protein FTO http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.6b00023/20160304/images/medium/bi-2016-00023r_0009.gif Biochemistry DOI: 10.1021/acs.biochem.6b00023 http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/bichaw/~4/B3hf_VejST0 More...	nmrlearner	Journal club	0	03-05-2016 11:21 AM
NIH Postdoctoral Position Available: NMR/MRI Studies of Cartilage and Muscle Aging, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States NIH Postdoctoral Position Available: NMR/MRI Studies of Cartilage and Muscle Aging, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States A postdoctoral position is available in the Magnetic Resonance Imaging and Spectroscopy Section (Richard Spencer, Chief) of the National Institute on Aging of the National Institutes of Health, located in Baltimore, Maryland. The work will center on... More...	nmrlearner	Job marketplace	0	02-05-2013 09:51 PM
Simultaneous acquisition of PAR and PAIN spectra Simultaneous acquisition of PAR and PAIN spectra Abstract We present a scheme that allows the simultaneous detection of PAR and PAIN correlation spectra in a single two-dimensional experiment. For both spectra, we obtain almost the same signal-to-noise ratio as if a PAR or PAIN spectrum is recorded separately, which in turn implies that one of the spectra may be considered additional information for free. The experiment is based on the observation that in a PAIN experiment, the PAR condition is always also fulfilled. The performance is demonstrated experimentally using uniformly...	nmrlearner	Journal club	0	03-03-2012 01:39 AM
Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G() apolipoprotein J peptide using solution NMR. Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G() apolipoprotein J peptide using solution NMR. Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G(*) apolipoprotein J peptide using solution NMR. Biochim Biophys Acta. 2011 Jan;1808(1):498-507 Authors: Mishra VK, Palgunachari MN, Hudson JS, Shin R, Keenum TD, Krishna NR, Anantharamaiah GM The surprising observation that a 10-residue class G(?) peptide from apolipoprotein J, apoJ, possesses...	nmrlearner	Journal club	0	03-08-2011 01:40 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off