The binding of the small heat-shock protein ?B-crystallin to fibrils of ?-synuclein is driven by entropic forces - pnas.org

		BioNMR > NMR community > Online News
The binding of the small heat-shock protein ?B-crystallin to fibrils of ?-synuclein is driven by entropic forces - pnas.org

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

10-26-2021, 01:10 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,779

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

The binding of the small heat-shock protein ?B-crystallin to fibrils of ?-synuclein is driven by entropic forces - pnas.org

The binding of the small heat-shock protein ?B-crystallin to fibrils of ?-synuclein is driven by entropic forces - pnas.org

The binding of the small heat-shock protein ?B-crystallin to fibrils of ?-synuclein is driven by entropic forces pnas.org Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Insights into heat shock protein machinery could point to interventions for neurodegenerative disease \| National Academy of Sciences - pnas.org Insights into heat shock protein machinery could point to interventions for neurodegenerative disease \| National Academy of Sciences - pnas.org Insights into heat shock protein machinery could point to interventions for neurodegenerative disease \| National Academy of Sciences pnas.org Read here	nmrlearner	Online News	0	07-03-2021 08:12 PM
Insights into heat shock protein machinery could point to interventions for neurodegenerative disease - pnas.org Insights into heat shock protein machinery could point to interventions for neurodegenerative disease - pnas.org Insights into heat shock protein machinery could point to interventions for neurodegenerative disease pnas.org Read here	nmrlearner	Online News	0	11-26-2020 07:18 AM
Specific Binding of Tetratricopeptide Repeat Proteinsto Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90)Is Regulated by Affinity and Phosphorylation Specific Binding of Tetratricopeptide Repeat Proteinsto Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90)Is Regulated by Affinity and Phosphorylation http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.5b00801/20151125/images/medium/bi-2015-00801d_0008.gif Biochemistry DOI: 10.1021/acs.biochem.5b00801 http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/bichaw/~4/YvFol5JSODc More...	nmrlearner	Journal club	0	11-26-2015 12:22 PM
Small Heat Shock Protein As Model for Alzheimer's Medication - Scicasts (press release) (blog) Small Heat Shock Protein As Model for Alzheimer's Medication - Scicasts (press release) (blog) http://www.bionmr.com//t1.gstatic.com/images?q=tbn:ANd9GcQ9moy7bI6-CN006Z0Ht_YPEwpfVDX7qETMgRnwpztgVdqHvywdHobvblWhtaMWJLlFb1Qq4Dw Scicasts (press release) (blog) <img alt="" height="1" width="1"> Small Heat Shock Protein As Model for Alzheimer's Medication Scicasts (press release) (blog) As Reif and his colleagues have discovered, it binds protein types that, unlike the beta-amyloid, clump together in an unordered manner. The researchers will be supported by the new NMR Center that is...	nmrlearner	Online News	0	10-23-2015 02:14 PM
Researchers uncover how small heat shock protein interacts with other proteins - News-Medical.net Researchers uncover how small heat shock protein interacts with other proteins - News-Medical.net <img alt="" height="1" width="1"> Researchers uncover how small heat shock protein interacts with other proteins News-Medical.net ... in uncovering precisely this mechanism. Using a refined procedure of solid-state nuclear magnetic resonance spectroscopy (solid-state NMR), they managed, for the first time ever, to identify the sites in the alpha-B-crystallin that attach to the ... and more » Read here	nmrlearner	Online News	0	10-16-2015 12:49 AM
Small Heat Shock Protein As Model for Alzheimer Medication - Scicasts (press release) (blog) Small Heat Shock Protein As Model for Alzheimer Medication - Scicasts (press release) (blog) http://www.bionmr.com//t1.gstatic.com/images?q=tbn:ANd9GcQ9moy7bI6-CN006Z0Ht_YPEwpfVDX7qETMgRnwpztgVdqHvywdHobvblWhtaMWJLlFb1Qq4Dw Scicasts (press release) (blog) <img alt="" height="1" width="1"> Small Heat Shock Protein As Model for Alzheimer Medication Scicasts (press release) (blog) As Reif and his colleagues have discovered, it binds protein types that, unlike the beta-amyloid, clump together in an unordered manner. The researchers will be supported by the new NMR Center that is currently...	nmrlearner	Online News	0	10-14-2015 12:47 PM
Small heat shock protein as model for Alzheimer's medication - News-Medical.net Small heat shock protein as model for Alzheimer's medication - News-Medical.net http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcSs_jrKR5ICaGu4iH3hpUBJnSF5w-iMfF0Qy_VGXVCtMo1BC7oe7a7d_oQiN2r1yXeRz2_shIs News-Medical.net <img alt="" height="1" width="1"> Small heat shock protein as model for Alzheimer's medication News-Medical.net Using a refined procedure of solid-state nuclear magnetic resonance spectroscopy (solid-state NMR), they managed, for the first time ever, to identify the sites in the alpha-B-crystallin that attach to the beta-amyloid. It is the first direct...	nmrlearner	Online News	0	10-13-2015 05:51 AM
Probing Dynamic Conformationsof the High-Molecular-Weight?B-Crystallin Heat Shock Protein Ensemble by NMR Spectroscopy Probing Dynamic Conformationsof the High-Molecular-Weight?B-Crystallin Heat Shock Protein Ensemble by NMR Spectroscopy Andrew J. Baldwin, Patrick Walsh, D. Flemming Hansen, Gillian R. Hilton, Justin L. P. Benesch, Simon Sharpe and Lewis E. Kay http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja307874r/aop/images/medium/ja-2012-07874r_0005.gif Journal of the American Chemical Society DOI: 10.1021/ja307874r http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/jacsat/~4/qcs9RnHBiBY	nmrlearner	Journal club	0	09-08-2012 08:44 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off