[ASAP] Assessing Site-Specific Enhancements Imparted by Hyperpolarized Water in Folded and Unfolded Proteins by 2D HMQC NMR
Assessing Site-Specific Enhancements Imparted by Hyperpolarized Water in Folded and Unfolded Proteins by 2D HMQC NMR
Or Szekely†?, Gregory Lars Olsen†§, Mihajlo Novakovic†, Rina Rosenzweig‡, and Lucio Frydman*†
https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/jacs.0c00807/20200512/images/medium/ja0c00807_0012.gif
Journal of the American Chemical Society
DOI: 10.1021/jacs.0c00807
http://feeds.feedburner.com/~r/acs/jacsat/~4/Wg_2GlL7qPY
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05-12-2020 08:32 PM
[NMR paper] Assessing site-specific enhancements imparted by hyperpolarized water in folded and unfolded proteins by 2D HMQC NMR.
Assessing site-specific enhancements imparted by hyperpolarized water in folded and unfolded proteins by 2D HMQC NMR.
Related Articles Assessing site-specific enhancements imparted by hyperpolarized water in folded and unfolded proteins by 2D HMQC NMR.
J Am Chem Soc. 2020 Apr 27;:
Authors: Szekely O, Olsen GL, Novakovic M, Rosenzweig R, Frydman L
Abstract
Dissolution DNP of hyperpolarized water can be a valuable aid in biomolecular NMR. With suitable optimizations one can utilize it to achieve, under near-physiological...
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04-28-2020 05:29 PM
Hyperpolarized MAS NMR of unfolded and misfolded proteins #DNPNMR
From The DNP-NMR Blog:
Hyperpolarized MAS NMR of unfolded and misfolded proteins #DNPNMR
König, Anna, Daniel Schölzel, Boran Uluca, Thibault Viennet, Ümit Akbey, and Henrike Heise. “Hyperpolarized MAS NMR of Unfolded and Misfolded Proteins.” Solid State Nuclear Magnetic Resonance 98 (April 2019): 1–11.
https://doi.org/10.1016/j.ssnmr.2018.12.003.
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03-24-2019 10:41 PM
[NMR paper] High-Resolution NMR of Folded Proteins in Hyperpolarized Physiological Solvents.
High-Resolution NMR of Folded Proteins in Hyperpolarized Physiological Solvents.
Related Articles High-Resolution NMR of Folded Proteins in Hyperpolarized Physiological Solvents.
Chemistry. 2018 Jul 03;:
Authors: Kaderavek P, Ferrage F, Bodenhausen G, Kurzbach D
Abstract
We report hyperpolarized 2D exchange spectroscopy (HYPEX) to obtain high-resolution nuclear magnetic resonance (NMR) spectra of folded proteins under near-physiological conditions. The technique is based on hyperpolarized water, which is prepared by dissolution...
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07-06-2018 09:40 AM
Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase
From The DNP-NMR Blog:
Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase
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Wang, Y., M. Ragavan, and C. Hilty, Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase. J. Biomol. NMR, 2016. 65(1): p. 41-48.
http://dx.doi.org/10.1007/s10858-016-0037-x
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05-15-2017 04:34 PM
Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase
Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase
Abstract
Proteinâ??ligand interaction is often characterized using polarization transfer by the intermolecular nuclear Overhauser effect (NOE). For such NOE experiments, hyperpolarization of nuclear spins presents the opportunity to increase the spin magnetization, which is transferred, by several orders of magnitude. Here, folic acid, a ligand of dihydrofolate reductase (DHFR), was hyperpolarized on 1H spins using dissolution dynamic nuclear polarization...
Assessing Site-Specific Enhancements Imparted by Hyperpolarized Water in Folded and Unfolded Proteins by 2D HMQC NMR - ACS Publications
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