Analyzing dynamic proteins MIT NewsMIT chemistry professor Mei Hong develops new techniques for studying the dynamic structures of proteins embedded in cell membranes.
Analyzing protein structures in their native environment - MIT News
Analyzing protein structures in their native environment - MIT News
Analyzing protein structures in their native environment MIT NewsProteins can fold in different ways depending on their environment. These different configurations change the function of the protein; misfolding is frequently ...
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01-07-2019 05:49 AM
Analyzing dynamic proteins - MIT News
Analyzing dynamic proteins - MIT News
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Analyzing dynamic proteins
MIT News
For her PhD thesis, Hong used NMR to study how phospholipids, the major building blocks of membranes, take on their shapes. These molecules consist of fatty tails that face inward and protein heads that face outward. This research helped prepare her ...
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08-08-2016 12:19 PM
Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar - News-Medical.net
Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar - News-Medical.net
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Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar
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In my lab, we focus on understanding structure, assembly and regulation of the LC8 protein interaction network, the array of LC8 interactions with diverse partners which affect multiple cellular functions in...
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02-18-2016 08:10 PM
Analyzing protein structures in their native environment - MIT News
Analyzing protein structures in their native environment - MIT News
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MIT News
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Analyzing protein structures in their native environment
MIT News
Until now, it has been difficult to fully characterize the different structures that proteins can take on in their natural environments. However, using a new technique known as sensitivity-enhanced nuclear magnetic resonance (NMR), MIT researchers have ...
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11-22-2015 01:36 AM
More Dynamic Protein Profiling - Genetic Engineering & Biotechnology News
More Dynamic Protein Profiling - Genetic Engineering & Biotechnology News
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Genetic Engineering & Biotechnology News
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More Dynamic Protein Profiling
Genetic Engineering & Biotechnology News
â??As a tool for preventing unnecessary work on the structure determination side, we introduced the 'NMR Profile' for identifying, from among the many proteins that we screen, those that are available as a structure-quality solution and...
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09-02-2015 05:44 AM
[NMR paper] Analyzing protein-ligand interactions by dynamic NMR spectroscopy.
Analyzing protein-ligand interactions by dynamic NMR spectroscopy.
Related Articles Analyzing protein-ligand interactions by dynamic NMR spectroscopy.
Methods Mol Biol. 2013;1008:243-66
Authors: Mittermaier A, Meneses E
Abstract
Nuclear magnetic resonance (NMR) spectroscopy can provide detailed information on protein-ligand interactions that is inaccessible using other biophysical techniques. This chapter focuses on NMR-based approaches for extracting affinity and rate constants for weakly binding transient protein complexes with lifetimes...
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06-05-2013 06:53 PM
Bruker and Berkeley Lab Combine NMR with SAXS for Analyzing Large Protein ... - Genetic Engineering News
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Bruker and Berkeley Lab Combine NMR with SAXS for Analyzing Large Protein ...
Genetic Engineering News
Bruker and Lawrence Berkeley National Laboratory are collaborating to develop structural biology methods and tools that integrate small-angle x-ray scattering (SAXS) technology with nuclear magnetic resonance (NMR). The aim is to generate a set of data ...
Bruker and Lawrence Berkeley National Laboratory Collaborate on Novel ...MarketWatch (press release)
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11-11-2011 08:26 AM
Bruker and Berkeley Lab Combine NMR with SAXS for Analyzing Large Protein ... - Genetic Engineering News
Bruker and Berkeley Lab Combine NMR with SAXS for Analyzing Large Protein ... - Genetic Engineering News
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Bruker and Berkeley Lab Combine NMR with SAXS for Analyzing Large Protein ...
Genetic Engineering News
The aim is to generate a set of data analysis algorithms for determining the structures of larger, multi-domain proteins and protein complexes with DNA, RNA or other proteins. The organizations claim that combining the NMR-derived 3-dimensional atomic ...
Bruker and Lawrence...