Prof. Konstantin Pervushin's NMR group

[markber]

Prof. Konstantin Pervushin affiliation:
Structural Biology
Biozentrum, University of Basel
Basel / Switzerland



A copy of Porf. Pervushin's research interests from the group website:

Beyond addressing fundamental problems in NMR and structural biology, our long term goals include establishment of an intelligent electronic infrastructure for accumulation and dissemination of NMR knowledge and expertise. This software framework is aimed to automate complex NMR routines, making advanced NMR technology accessible to a wider range of Life Science specialists.

Publications

Full publication list via PubMed.
2010

• Nikolaev YV, Deillon C, Hoffmann SR, Bigler L, Friess S, Zenobi R, Pervushin K, Hunziker P, Gutte B. The Leucine Zipper Domains of the Transcription Factors GCN4 and c-Jun Have Ribonuclease Activity. PLoS ONE, 5(5), e10765.

• Senthamarai RR, Kuprov I, Pervushin K. Benchmarking NMR experiments: A relational database of protein pulse sequences. J Magn Reson, 203(1), 129-137.

2009

• Pervushin K, Tan E, Parthasarathy K, Lin X, Jiang FL, Yu D, Vararattanavech A, Soong TW, Liu DX, Torres J. Structure and inhibition of the SARS coronavirus envelope protein ion channel. PLoS Pathog, 5(7), e1000511.
• Biuković G, Gayen S, Pervushin K, Grüber G. Domain features of the peripheral stalk subunit H of the methanogenic A1AO ATP synthase and the NMR solution structure of H(1-47). Biophys J, 97(1), 286-94.
• Bai Y, Liu S, Jiang P, Zhou L, Li J, Tang C, Verma C, Mu Y, Beuerman RW, Pervushin K. Structure-dependent charge density as a determinant of antimicrobial activity of peptide analogues of defensin. Biochemistry, 48(30), 7229-39.
• Wei L, Pervushin K, Mu Y. Residual Structure in Islet Amyloid Polypeptide Mediates Its Interactions with Soluble Insulin. Biochemistry, 48(11), 2368–2376.

2008

• Wong LE, Masse JE, Jaravine V, Orekhov V, Pervushin K. Automatic assignment of protein backbone resonances by direct spectrum inspection in targeted acquisition of NMR data. J Biomol NMR, 42(2), 77-86.
• Pogoryelov D, Nikolaev Y, Schlattner U, Pervushin K, Dimroth P, Meier T. Probing the rotor subunit interface of the ATP synthase from Ilyobacter tartaricus. FEBS J, 275(19), 4850-62.
• Parthasarathy K, Ng L, Lin X, Liu DX, Pervushin K, Gong X, Torres J. Structural flexibility of the pentameric SARS coronavirus envelope protein ion channel. Biophys J, 95(6), L39-41.

2007

• Pervushin K, Vamvaca K, Vögeli B, Hilvert D. Structure and dynamics of a molten globular enzyme. Nat Struct Mol Biol, 14(12), 1202-6.
• Alioth S, Meyer S, Dutzler R, Pervushin K. The cytoplasmic domain of the chloride channel ClC-0: structural and dynamic characterization of flexible regions. J Mol Biol, 369(5), 1163-9.
• Nikolaev Y, Pervushin K. NMR Spin State Exchange Spectroscopy Reveals Equilibrium of Two Distinct Conformations of Leucine Zipper GCN4 in Solution. J Am Chem Soc, 129(20), 6461-6469.