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  #1  
Old 01-26-2010, 04:42 PM
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Default Answered: Decoupling, what modultaion frequency to use ?

Hi all,

Perhaps a stupid question, but so far no one answered this one to me.

I want to find out what decoupler modulation frequency (dmf in Varian syntax) is needed to properly decouple observed couplings. Can anyone tell me ? I am looking for a practical answer.

I found a paper on decoupling, i.e. Shaka, A.J., Keeler, J. (1987): Progr. NMR Spectroscopy, 19, 47-129. Although this paper is formally correct, it is also very hard to read.

So let's make a practical example:
On an 800MHz machine, the carrier is on water (4.5 ppm), and there are imino protons resonating at 12-14 ppm. (JNH = ~40 Hz)
I want to observe nicely decoupled signals for these imino protons.
What decoupler modulation frequency is required to properly decouple these protons ?

P.S. I realize (of course) that the pulse-power has to be adjusted as we decouple.
(If requires, assume a hard 90-degrees pulse takes 8 us at 60dB)

Regards,
Ramon
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Best Answer - Posted by warner
You've probably figured this out by now, but for the future, here is a nice document regarding decoupling on Varian.
http://cunmr800.colorado.edu/documen...Decoupling.pdf

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Old 12-13-2010, 06:56 AM
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Default

You've probably figured this out by now, but for the future, here is a nice document regarding decoupling on Varian.
http://cunmr800.colorado.edu/documen...Decoupling.pdf
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