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Protein Structures Give Disease Clues - Bioscience Technology
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Protein Structures Give Disease Clues
Bioscience Technology
Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules â?? potentially leading to new ways to treat ...
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nmrlearner
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02-02-2012 09:43 PM
[NMR paper] Elucidation of the protein folding landscape by NMR.
Elucidation of the protein folding landscape by NMR.
Related Articles Elucidation of the protein folding landscape by NMR.
Methods Enzymol. 2005;394:299-321
Authors: Dyson HJ, Wright PE
NMR is one of the few experimental methods that can provide detailed insights into the structure and dynamics of unfolded and partly folded states of proteins. Mapping the protein folding landscape is of central importance to understanding the mechanism of protein folding. In addition, it is now recognized that many proteins are intrinsically unstructured in...
nmrlearner
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11-24-2010 11:14 PM
[NMR paper] Unfolded proteins and protein folding studied by NMR.
Unfolded proteins and protein folding studied by NMR.
Related Articles Unfolded proteins and protein folding studied by NMR.
Chem Rev. 2004 Aug;104(8):3607-22
Authors: Dyson HJ, Wright PE
nmrlearner
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11-24-2010 10:01 PM
[NMR paper] Kinetic studies of protein folding using NMR spectroscopy.
Kinetic studies of protein folding using NMR spectroscopy.
Related Articles Kinetic studies of protein folding using NMR spectroscopy.
Nat Struct Biol. 1998 Jul;5 Suppl:504-7
Authors: Dobson CM, Hore PJ
nmrlearner
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11-17-2010 11:15 PM
[NMR paper] Contacting the protein folding funnel with NMR.
Contacting the protein folding funnel with NMR.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--highwire.stanford.edu-icons-externalservices-pubmed-custom-pnas_full_free.gif http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.pubmedcentral.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.gif Related Articles Contacting the protein folding funnel with NMR.
Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7129-31
Authors: Onuchic JN
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08-22-2010 05:08 PM
[NMR paper] Insights into protein folding from NMR.
Insights into protein folding from NMR.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--arjournals.annualreviews.org-images-AnnualReviews100x25.gif Related Articles Insights into protein folding from NMR.
Annu Rev Phys Chem. 1996;47:369-95
Authors: Dyson HJ, Wright PE
NMR has emerged as an important tool for studies of protein folding because of the unique structural insights it can provide into many aspects of the folding process. Applications include measurements of kinetic folding events and structural characterization of folding...
nmrlearner
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08-22-2010 02:27 PM
[NMR paper] Following protein folding in real time using NMR spectroscopy.
Following protein folding in real time using NMR spectroscopy.
Related Articles Following protein folding in real time using NMR spectroscopy.
Nat Struct Biol. 1995 Oct;2(10):865-70
Authors: Balbach J, Forge V, van Nuland NA, Winder SL, Hore PJ, Dobson CM
The refolding of apo bovine alpha-lactalbumin has been monitored in real time by NMR spectroscopy following rapid in situ dilution of a chemically denatured state. By examining individual resonances in the time-resolved NMR spectra, the native state has been shown to emerge in a cooperative...
nmrlearner
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08-22-2010 03:50 AM
[NMR paper] Prelude to NMR studies of protein folding.
Prelude to NMR studies of protein folding.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.nature.com-images-lo_nsb.gif Related Articles Prelude to NMR studies of protein folding.
Nat Struct Biol. 1999 Jul;6(7):608
Authors: Smith T
Protein folding technology
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