[MWClarkson blog] Dynamics conservation in the Ras superfamily
Dynamics conservation in the Ras superfamily
http://www.researchblogging.org/public/citation_icons/rb2_large_gray.pngThe proposition that general fold architecture is preserved within a family of evolutionarily-related proteins is not controversial. The amino acid sequence of a protein determines its structure, and countless studies have substantiated the idea that proteins with similar sequences will adopt similar folded conformations. Because structure and dynamics are intrinsically linked, one could reasonably assume that many features of a protein's dynamics get conserved along with...