HELLO all nmr wikier,I am facing problem in runing topshim on bruker 500Mhz using topspin 2.1 it finishes with error (field map-signal to noise is too low) while previously I was using quite comprehensively.Topshim is working in 3d shiming and 1d shiming on sucrose sample but not working on 0.1% E.B sample.I have loaded the right shimfile and it is giving good s/n ratio same as was in acceptance test.It is also creating problem in rga it takes several attempt and set rga little bit lower even for strong sample does any body know where is the problem.Thanks in advance for answering.
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