I get the feeling that most physical/biological science types don’t keep blogs as much as other disciplines, although I would be happy if I am completely mistaken in this. That being said, does anyone have any suggestions of individuals’ or groups’ blogs about NMR specifically, but more broadly about biophysics, or structural biology, or anything along those lines? The only things I have found to follow are Sandwalk , Everyday Scientist , Chemical Musings , and the Disgruntled and Skeptical chemists. All are interesting, and Sandwalk has a series going on protein folding, but none are quite what I’m looking for. Perhaps I don’t even know what I’m looking for.
NMR Structural Biology and Biophysics of Protein:Protein Complexes, National Cancer Institute, Frederick, MD, United States
NMR Structural Biology and Biophysics of Protein:Protein Complexes, National Cancer Institute, Frederick, MD, United States
Postdoctoral positions are available in the Macromolecular NMR section of the Structural Biophysics Laboratory headed by Dr. R. Andrew Byrd at the National Cancer Institute. The Byrd lab combines NMR structural biology & Small Angle Xray Scattering (...
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nmrlearner
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11-15-2011 11:36 PM
Random phase detection in multidimensional NMR [Biophysics and Computational Biology]
Random phase detection in multidimensional NMR
Maciejewski, M. W., Fenwick, M., Schuyler, A. D., Stern, A. S., Gorbatyuk, V., Hoch, J. C....
Date: 2011-10-04
Despite advances in resolution accompanying the development of high-field superconducting magnets, biomolecular applications of NMR require multiple dimensions in order to resolve individual resonances, and the achievable resolution is typically limited by practical constraints on measuring time. In addition to the need for measuring long evolution times to obtain high resolution, the need to distinguish the sign of the frequency...
nmrlearner
Journal club
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10-04-2011 08:47 PM
Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion [Biophysics and Computational Biology]
Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion
Meinhold, D. W., Wright, P. E....
Date: 2011-05-31
Detailed understanding of protein function and malfunction hinges on the ability to characterize transiently populated states and the transitions between them. Here, we use 15N, , and 13CO NMR R2 relaxation dispersion to investigate spontaneous unfolding and refolding events of native apomyoglobin. Above pH 5.0, dispersion is dominated by processes involving fluctuations of the F-helix region, which...
nmrlearner
Journal club
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05-31-2011 11:41 PM
Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method [Biophysics and Computational Biology]
Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method
Verardi, R., Shi, L., Traaseth, N. J., Walsh, N., Veglia, G....
Date: 2011-05-31
Phospholamban (PLN) is a type II membrane protein that inhibits the sarcoplasmic reticulum Ca2+-ATPase (SERCA), thereby regulating calcium homeostasis in cardiac muscle. In membranes, PLN forms pentamers that have been proposed to function either as a storage for active monomers or as ion channels. Here, we report the T-state structure of pentameric PLN solved by a hybrid solution and...
nmrlearner
Journal club
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05-31-2011 11:41 PM
Mapping allostery through the covariance analysis of NMR chemical shifts [Biophysics and Computational Biology]
Mapping allostery through the covariance analysis of NMR chemical shifts
Selvaratnam, R., Chowdhury, S., VanSchouwen, B., Melacini, G....
Date: 2011-04-12
Allostery is a fundamental mechanism of regulation in biology. The residues at the end points of long-range allosteric perturbations are commonly identified by the comparative analyses of structures and dynamics in apo and effector-bound states. However, the networks of interactions mediating the propagation of allosteric signals between the end points often remain elusive. Here we show that the covariance analysis of NMR chemical...
nmrlearner
Journal club
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04-13-2011 01:15 AM
[Nature network NMR forum] Biophysics congress in Lisbon in July 2008 (0 replies)
Biophysics congress in Lisbon in July 2008 (0 replies)
We would like to remind you about the 1st Portuguese-Spanish-British Biophysical Congress, which will take place at Parque das Nações, in
Lisbon, between 10th and 13th July 2008. This is the first time that we are organising a joint congress with these three Biophysical Societies and we think that this scientific reunion will be quite interesting and stimulating. I would like to invite you to visit the web page of the Congress and to register at the same time. The deadline to submit abstracts is June, 8th, 2008, so you need...
nmrlearner
News from other NMR forums
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08-21-2010 03:29 PM
[Nature network NMR forum] Journal club: structural biology of HIV infection (0 replies)
Journal club: structural biology of HIV infection (0 replies)
A recent paper in Science highlights once again the potential of NMR to yield insights into complex molecular recognition events in critical biological processes.
In this case the authors used a combination of X-ray crystallography and NMR to probe the structure of the extracellular terminus of the CCR5 co-receptor which, in concert with human CD4 and HIV gp120, is crucial for viral entry. The authors applied challenging saturation transfer effects to study the structure of a small synthetic peptide in a ternary...
nmrlearner
News from other NMR forums
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08-21-2010 03:29 PM
Faculty Position - Structural Biology and Biophysics - University of Connecticut
Hi, I found this job advertised in Science Magazine (sciencemag.org)
Job Title: Faculty Position - Structural Biology and Biophysics
Employer: University of Connecticut
Job Location: Storrs, Connecticut, United States
The Department of Molecular and Cell Biology at the University of Connecticut invites applications for a TENURE-TRACK ASSISTANT PROFESSOR in the area of Structural Biology and Biophysics. The ideal applicant will employ structural and biophysical approaches such as biomolecular NMR, single-molecule spectroscopy, computational structural biology or high resolution...